Download CDKL3, Cyclin-dependent kinase-like 3 (NKIAMRE) polyclonal

CDKL3, Cyclin-dependent kinase-like 3
(NKIAMRE) polyclonal antibody
F
or Research Use Only. Not for
Diagnostic or Therapeutic Use.
Purchase does not include or carry
any right to resell or transfer this
product either as a stand-alone
product or as a component of another
product. Any use of this product other
than the permitted use without the
express written authorization of Allele
Biotech is strictly prohibited
Website: www.allelebiotech.com
Call: 1-800-991-RNAi/858-587-6645
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Email: [email protected]
C
yclin-dependent kinase-like 3 (CDKL3) protein is a member
of cyclin-dependent protein kinase (CDK) family. CDK family members are important regulators of cell cycle progression.
CDKL3 is absent in leukemic patients with a chromosome 5q
deletion. This loss may be an important determinant of dysmyelopoiesis. The precise biological function of CDKL3 has not
been determined yet.
Buffers
Purified rabbit polyclonal antibody supplied in PBS with 0.09%
(W/V) sodium azide. This antibody is purified through a protein
G column and eluted out with both high and low pH buffers and
neutralized immediately after elution then followed by dialysis
against PBS.
Immunogen
Box 1 | Basic Info
N/A
Cat. No.
ABP-PAB-10174
Animal ID
RC40104
Application
Host
Rabbit
Tested by peptide-specific ELISA (1:1,000).
Reactivity
Human
Format
Purified
Accession number
NM_016508
Amount
100µg
Alternative Name(s):
Storage
Maintain refrigerated at 2-8ºC for up to 6 months. For long
term storage store at -20ºC. Avoid repeated freeze-thaw
cycles.
serine-threonine protein kinase NKIAMRE
References:
1. Yee KW, Moore SJ, Midmer M,
Zanke BW, Tong F, Hedley D, Minden
MD: NKIAMRE, a novel conserved
CDC2-related kinase with features of
both mitogen-activated protein kinases
and cyclin-dependent kinases. Biochem. Biophys. Res. Commun. 308(4):
784-792 (2003).
2. Midmer M, Haq R, Squire JA, Zanke
BW: Identification of NKIAMRE, the
human homologue to the mitogen-activated protein kinase-/cyclin-dependent
kinase-related protein kinase NKIATRE,
and its loss in leukemic blasts with
chromosome arm 5q deletion. Cancer
Res. 59(16): 4069-4074 (1999).
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