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Name: ________________________________________ Period: _____ Date: ______________________
Immune System Review
WARNING: This is not intended to be used solely as a study guide; you should also reference
your notes and materials used in class.
True or False
_______1. The skin is the first line of defense against pathogens.
_______2. Sneezing is a method of removing pathogens from your nose.
_______3. Sweat, mucus, tears, saliva, and white blood cells are all types of barriers used to
protect you and are used in the second line of defense.
_______4. The inflammatory response is part of the body’s first line of defense.
_______5. Leukocytes are white blood cells that fight infections and get rid of debris.
_______6. The second line of defense attacks pathogens that manage to enter the body.
_______7. The first line of defense includes the inflammatory response and phagocytes.
_______8. A nonspecific defense can target a particular pathogen.
_______9. The inflammatory response releases chemicals called histamines.
______10. The third line of defense is referred to as the immune response.
______11. Antibodies trigger the immune system to react against the cells that carry them.
______12. Antibodies are large Y-shaped proteins that recognize and bind to antigens.
______13. Immunization is a form of passive immunity.
______14. Autoimmune diseases occur when the immune system attacks itself.
______15. Allergies can be very dangerous, even life-threatening.
______16. Histamines can reduce or eliminate the effects of the antihistamines that cause
allergy symptoms.
______17. A immune response can occur in people who have undergone organ transplant,
attacking the transplanted organ.
______18. AIDS is a virus that attacks the endocrine system.
Multiple Choice
19. Which statement best describes the immune system?
(a) The immune system produces gametes.
(b) The immune system exchanges gases between the blood and lungs.
(c) The immune system protects the body from pathogens.
(d) The immune system digests food into usable nutrients.
20. The immune system is comprised of _______________lines of defense.
(a) two
(b) three
(c) four
(d) five
21. Which statement best describes the first line of defense?
(a) The first line of defense consists of different types of barriers that keep most
pathogens out the body.
(b) The first line of defense includes the inflammatory response.
(c) Leukocytes are the cells responsible for the first line of defense.
(d) The first line of defense includes the skin, mucous membranes and biological barriers
such as white blood cells.
22. Which statement describes the second line of defense?
(a) The second line of defense includes biological and chemical barriers.
(b) The skin is the major organ of the second line of defense.
(c) The second line of defense keeps most pathogens out of the body
(d) The second line of defense is encountered by pathogens that enter the body.
23. What is the inflammatory response?
(a) The inflammatory response is when histamines are produced.
(b) The inflammatory response is the body’s first reaction of the body to infection.
(c) The inflammatory response is a chemical barrier that destroys pathogens on the
body surface.
(d) none of the above
24. Phagocytes
(a) are leukocytes (white blood cells) that engulf and break down pathogens and debris
(b) are chemical barriers that destroy pathogens
(c) are part of the first line of defense
(d) all of the above
25. The immune response
(a) is a specific to a particular pathogen
(b) is the third line of defense
(c) allows the immune system to “remember” the pathogen after the infection is over
(d) all of the above
26. Active immunity
(a) can last a lifetime
(b) can result from an immunization
(c) results when an immune response to a pathogen produces memory cells
(d) all of the above
27. An autoimmune disease
(a) occurs when the immune system initiates an immune response against foreign
(b) occurs when the immune system attacks the body’s own pathogens
(c) occurs when the immune system fails to recognize the body’s own molecules as
belonging to the person
(d) occurs when the immune system fails to recognize foreign molecules as belonging to
the person
28. Types 1 diabetes
(a) attacks the insulin-producing cells of the pancreas
(b) is an autoimmune disease
(c) results in high blood sugar levels
(d) all of the above
29. AIDS results from year of damage to the _________________system by HIV.
(a) nervous
(b) immune
(c) digestive
(d) endocrine
30. A patient with an autoimmune disease or receiving an organ transplant might be given this
type of medicine to decrease the immune system response.
(a) antibiotic’s
(b) immunosuppressant’s
(c) blood transfusion
(d) anti-viral’s
Short answer
31. What is meant by the first line of defense? Provide examples.
32. Describe how the body would protect itself from a second line of defense if you stepped a
rusty nail.