* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Chapter 37 Objectives and other Animal System Material
Survey
Document related concepts
Inflammation wikipedia , lookup
Lymphopoiesis wikipedia , lookup
Social immunity wikipedia , lookup
Immunocontraception wikipedia , lookup
Complement system wikipedia , lookup
Autoimmunity wikipedia , lookup
Monoclonal antibody wikipedia , lookup
DNA vaccination wikipedia , lookup
Adoptive cell transfer wikipedia , lookup
Molecular mimicry wikipedia , lookup
Hygiene hypothesis wikipedia , lookup
Immune system wikipedia , lookup
Adaptive immune system wikipedia , lookup
Immunosuppressive drug wikipedia , lookup
Cancer immunotherapy wikipedia , lookup
Innate immune system wikipedia , lookup
Transcript
Chapter Objectives: Chapter 43 the Immune System 1. 2. 3. 4. 5. Distinguish between innate and adaptive immunity. Explain nonspecific defense and list nonspecific lines of defense in vertebrate body Define cytokine. Explain how the physical barrier of skin is reinforced by chemical defenses. Explain how complement proteins may be activated and how they function in cooperation with other defense mechanisms 6. Define phagocytosis and list 2 types of phagocytic cells derived from white blood cells 7. Describe the inflammatory response pattern and how it is triggered 8. Explain how the inflammatory response prevents the spread of infection to surrounding tissue 9. List several chemical signals that initiate and mediate the inflammatory response 10. Describe several systemic reactions to infections and explain how they contribute to defense 11. What are MHC markers? 12. Diagram and label the structure of an antibody and explain how this structure allows antibodies to perform the following functions a. recognize and bind to antigens b. assist in destruction and elimination of antigens 13. Distinguish between variable (V) and constant (C) regions of an antibody molecule 14. Compare and contrast the structure and function of an enzyme's active site and an antibody's antigen-binding site 15. List the 5 major classes of antibodies (immunoglobulins-Ig’s) in mammals and distinguish among them 16. How does antigen diversity arise? 17. Explain how the immune response differs from nonspecific defenses 18. List and describe the 4 characteristics of adaptive immune responses 19. Outline the steps of antigen processing 20. Distinguish between primary and secondary immune response 21. Describe the mechanism of clonal selection 22. Describe the cellular basis for immunological memory 23. Explain how the humoral (antibody mediated immune response) response is provoked 24. Explain how B cells are activated 25. Outline a cell mediated immune response to a virus infected cell 26. Design a flow chart describing the major sequence of events that follows the interaction between antigen presenting macrophages and helper T cells, including both cell-mediated and humoral immunity 27. Describe how cytotoxic T cells recognize and kill their targets 28. Explain how the function of cytotoxic T cells differs from that of complement and natural killer cells 29. Distinguish between complement's classical and alternative activation pathways 30. Read p. 632-634 and for ABO blood groups a. list all possible combinations for donor and recipient in blood transfusions b. indicate which combinations would cause an immune response in the recipient c. state which blood type is the universal donor 31. Explain how the immune response to Rh factor differs from the response to A and B blood antigens 32. Outline the development of B and T lymphocytes from stem cells in red bone marrow 33. Describe the potential problem of Rh incompatibility between a mother and her unborn fetus and explain what precautionary measures may be taken 34. Describe an allergic reaction including the role of IgE, mast cells, and histamine 35. List some known autoimmune disorders and describe possible mechanisms of autoimmunity 36. Explain why immune-deficient individuals are more susceptible to cancer than normal individuals 37. Recall the infectious agent that causes AIDS and explain how it weakens the immune system 38. Explain how AIDS is transmitted and why it is difficult to produce vaccines to protect uninfected individuals 39. Describe what it means to be HIV-positive 40. Explain how general health and mental well being might affect the immune system Also read chapters 35, 36, and 38. You do not need to know details of bone, muscle, respiratory anatomy, but you need to start to make connections to the body as a whole. Chapter 35: Pay attention to 35-2 Invertebrate Skeletons; 35-7 Sliding Filament Theory; 35-8 Integration of Nervous and Muscular Systems; 35-9 Muscle Metabolism (we will integrate this with Cell Respiration). Chapter 36: Pay attention to 36-2 Overview and Evolution of Blood Circulation, You’re already reading 36-4, 36-5, and 36-6 for the Immune System, and 36-10 Mechanisms of Capillary Exchange Chapter 38: Pay attention to 38-2 Nature of Respiration and 38-7 Gas Exchange and Transport.