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DNA CFA A SB2. Students will analyze how biological traits are passed on to successive generations. a. Distinguish between DNA and RNA. b. Explain the role of DNA in storing and transmitting cellular information. c. Using Mendel’s laws, explain the role of meiosis in reproductive variability. d. Describe the relationships between changes in DNA and potential appearance of new traits including Alterations during replication. Insertions Deletions Substitutions Mutagenic factors that can alter DNA. High energy radiation (x-rays and ultraviolet) Chemical 1. RNA differs from DNA in that: a. it has a different kind of sugar b. it is single stranded c. it has uracil d. all of these 2. Which of the following is found on RNA but not DNA? a. uracil b. deoxyribose c. phosphate d. adenine 3. During replication, the DNA bases are AAT. The complimentary bases are: a. TTA b. UUA c. UUU d. CCC Figure 12-1 4. Figure 12-1 shows the structure of a(an) a. DNA molecule. b. amino acid. 5. The process by which DNA makes a copy of itself is called: b. synthesis b. replication c. transcription c. RNA molecule. d. protein. d. translation 6. The chemical unit of nucleic acid molecules that consist of a phosphate group, a sugar molecule, and a nitrogen base is known as: c. a nucleic acid b. a base c. a ribosome d. a nucleotide 7. The two men who established the structure of DNA were: d. Hershey and Chase b. Watson and Crick c. Avery and Griffith d. Chargaff 8. DNA replication results in: e. 2 completely new DNA molecules f. 2 DNA molecules that each contain a strand of the original and a new strand g. 1 new DNA molecule, 1 old molecule is conserved h. 1 new molecule of DNA 9. During replication, adenine joins with: a. adenine b. cytosine c. guanine d. thymine e. uracil 10. During replication, cytosine joins with: a. adenine b. cytosine c. guanine d. thymine e. uracil 11. In the process of replication, we find DNA ligase on a. the leading strand. b. the lagging strand. c. the ribosome. 12. The first major experiment that led to the discovery of DNA as genetic material was performed by a. Giffith b. Avery c. Hershey and Chase d. Watson and Crick 13. The person who analyzed the amount of adenine, guanine, thymine and cytosine in DNA was a. Chargaff b. Avery c. Hershey and Chase d. Watson and Crick 14. All ______________ bases have a double ring. a. pyrimidine b. purine c. DNA d. nitrogenous 15. All ______________ bases have a single ring. a. pyrimidine b. purine c. DNA d. nitrogenous 16. The outside “rails” or strands of DNA are made of alternating a. phosphates and sugars. b. cytosine and guanine. c. DNA and RNA. d. thymine and adenine. 17. If the orientation of the top strand of DNA is 5’ to 3’ then the orientation of the bottom rail is a. 5’ to 3’ b. 1’ to 3’ c. 3’ to 5’ d. 1’ to 5’ 18. One of the basic differences between a DNA nucleotide and a RNA nucleotide is: a. the kind of sugar molecule c. number of possible bases b. the kind of phosphate group d. there is no difference 19. One of the specific enzymes necessary for DNA replication is: a. RNA polymerase b. DNA polymerase c. replicationase d. none of these 20. The lagging strand of DNA is synthesized into small segments called a. DNA ligase. b. Okazaki fragments. c. helicase. d. DNA polymerase. 21. The enzyme that unzips and unwinds DNA during replication is a. DNA ligase. b. RNA polymerase. c. helicase. d. DNA polymerase. 22. The sequence of the template strand of DNA is AAGCTA. The nontemplate’s complementary strand is a. CCGCAT b. TTCGAT c. TTGCAT d. AACGAT Match the term with the definition 23. DNA a. ribonucleic acid 24. RNA b. A=T, C=G 25. Chargaff’s Rule c. a phosphate, a sugar and a base 26. double helix d. “twisted ladder” 27. nucleotide e. deoxyribonucleic acid 28. Once transcription has been completed, which of the following is NOT necessary for protein synthesis to occur? a. tRNA b. ribosomes c. mRNA d. DNA 29. Which site of the tRNA molecule binds to the mRNA molecule? a. anitcodon b. codon c. amino acid d. 5 prime end 30. RNA is synthesized on a DNA template in a process called _________, which utilizes the enzyme________. a. translation, RNA polymerase b. transcription, DNA polymerase c. transcription, RNA polymerase d. replication, DNA polymerase