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Transcript
The CIG invites you to Henrik Kaessmann’s farewell lecture « Functional evolution of mammalian genomes» Henrik Kaessmann Center for Integrative Genomics Auditorium C, Génopode UNIL - Lausanne Thursday September 24, 2015 5:30 PM Program ¾¾ Welcome Prof N.Hernandez ¾¾ Farewell Lecture Prof H.Kaessmann «Functional evolution of mammalian genomes» ¾¾ Refreshments will be served. Henrik Kaessmann Henrik Kaessmann, Professor at the Center for Integrative Genomics (CIG) of the University of Lausanne (UNIL), is an expert in the field of evolutionary genomics. The main goal of his research is the identification of molecular changes underlying the evolution of mammalian phenotypes. Given that regulatory mutations affecting gene expression probably explain most of phenotypic evolution, the work of his group work focuses on large-scale evolutionary analyses of gene expression patterns and underlying regulatory mechanisms across tissues from representative mammals and vertebrate outgroup species. He will leave UNIL in October for a professorship at the University of Heidelberg (Center for Molecular Biology). Mammals share major traits (e.g., lactation, hair and relatively large brains with unique structures), but have also evolved distinct anatomical, physiological 2014 – Present Full Professor, CIG, UNIL and behavioral characteristics, relating to differences in reproduction, life span, cognitive abilities and disease susceptibility. The molecular changes (i.e., changes 2010 – Present Group Leader, SIB in protein/RNA sequences or expression levels) underlying these phenotypic shifts 2007 – 2014 Associate Professor (with tenure), CIG, UNIL and the associated selective pressures have only recently begun to be investigated 2003 – 2007 Assistant Professor (tenure-track), CIG, UNIL based on an increasing number of available mammalian genomes. Henrik 2001 – 2003 Postdoctoral fellow (EMBO, Emmy Noether) Kaessmann’s group performs integrated bioinformatics analyses pertaining to the University of Chicago, USA functional evolution of mammalian genes (and potentially associated phenotypic changes) on the basis of publicly available genomic data as well as extensive data 1997 – 2001 Ph.D. degree (Summa cum laude), Max Planck Institute for Evolutionary Anthropology (e.g., large-scale transcriptome data) generated by the wet lab unit of the group. University of Leipzig, Germany His group has been interested in a range of topics related to the functional 1997 Master of Science degree, Uppsala University evolution of genomes from primates (e.g., the emergence of new genes and their Sweden functions) and other mammals (e.g., the origin and evolution of mammalian sex 1995 – 1997 Biology studies, Uppsala University chromosomes). In the framework of projects launched in 2009, his group has Sweden been producing large amounts of transcriptome and genome (e.g., epigenome) 1992 – 1994 Biology studies, Ludwig Maximilians University data for a unique collection of tissues from representative mammals and outgroup Munich, Germany species (e.g., birds) using next generation sequencing technologies. Topics of current projects that are based on these data include the origins and/or evolution of protein-coding genes, alternative splicing, microRNAs, long noncoding RNAs, and sex chromosomes (e.g., X dosage compensation and Y origins and functions). © Felix Imhof From 2015 (October) Full Professor, CMB, University of Heidelberg Germany