Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Action potential wikipedia , lookup
Chemical synapse wikipedia , lookup
Theories of general anaesthetic action wikipedia , lookup
Lipid bilayer wikipedia , lookup
Membrane potential wikipedia , lookup
Organ-on-a-chip wikipedia , lookup
Cytokinesis wikipedia , lookup
SNARE (protein) wikipedia , lookup
Model lipid bilayer wikipedia , lookup
List of types of proteins wikipedia , lookup
Insights into structure of Golgi apparatus ******************************************** Using theory of membrane bending elasticity and a contact attractive intermembrane potential, we study stacks of lipid vesicles as models of the Golgi apparatus. By minimizing the energy of the stack at fixed total membrane area and volume, we allow the cisternae that form the apparatus to exchange their area and volume so as to adjust their individual shapes: This captures some features of the apparatus as a dynamical structure. We systematically explore several nontrivial topologies of cisternae to elucidate the structural role of the openings in the cisternae called fenestrations. Our results suggest that they may be responsible for the flattened shape of the Golgi apparatus. We also discuss other aspects of the complex architecture of this cell organelle.