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Download Practice Questions: Statistics, 4.1 and 4.2 (SL) 8. What does the
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Practice Questions: Statistics, 4.1 and 4.2 (SL) 8. What does the following scatter graph show? A. No correlation between these variables B. Strong positive correlation between these variables C. Strong negative correlation between these variables D. Weak negative correlation between these variables (Total 1 mark) 9. The t-test is used to test the statistical significance of a difference. What is that difference? A. Between observed and expected results B. Between the means of two samples C. Between the standard deviation of two samples D. Between the size of two samples (Total 1 mark) 6. Rice (Oryza sativa) is usually intolerant to sustained submergence under water, although it grows rapidly in height for a few days before dying. This is true for one variety, Oryza sativa japonica. The variety Oryza sativa indica is much more tolerant to submergence. Three genetically modified forms of O. sativa japonica, GMFA, GMFB and GMFC, were made using different fragments of DNA taken from O. sativa indica. The plants were then submerged for a period of 11 days. The heights of all the plants were measured at the beginning and at the end of the submergence period. [Adapted by permission from Macmillan Publishers Ltd, Xu et al. 2006. “Sub1A is an ethyleneresponse-factor-like gene that confers submergence tolerance to rice.” Nature. Vol 442. Pp 705– 708. Copyright 2006. http://www.nature.com/] (a) (i) State which group of rice plants were the shortest at the beginning of the experiment. ............................................................................................................. .............. (1) 1. Which of the following statements about homologous chromosomes is correct? A. Each gene is at the same locus on both chromosomes. B. They are two identical copies of a parent chromosome which are attached to one another at the centromere. C. They always produce identical phenotypes. D. They are chromosomes that have identical genes and alleles. (Total 1 mark) 2. What happens in crossing over? A. Exchange of genetic material between homologous chromosomes B. Exchange of genes during metaphase of mitosis C. Random distribution of chromosomes during meiosis D. Homologous chromosomes fail to separate during meiosis (Total 1 mark) (ii) Calculate the percentage change in height for the O. sativa japonica unmodified variety during the submergence period. Show your working. ............................................................................................................. .............. ............................................................................................................. .............. ............................................................................................................. .............. ............................................................................................................. .............. ............................................................................................................. .............. (2) (b) Explain how the error bars can be used to compare the results for O. sativa indica. ....................................................................................................................... ............... ....................................................................................................................... ............... ....................................................................................................................... ............... ....................................................................................................................... ............... ....................................................................................................................... ............... (2) (c) Deduce the general relationship between the growth of all the japonica varieties and their stated tolerance level. ....................................................................................................................... ............... ....................................................................................................................... ............... (1) 4. Which of the following types of information are needed to construct a karyotype? I. Size of the chromosomes II. Gene mutations of the chromosomes III. Age of the individual A. I only B. II only C. I and II only D. I, II and III (Total 1 mark) 27. Which of the following is the cause of sickle-cell anemia? A. Tryptophan is replaced by leucine. B. Leucine is replaced by valine. C. Glutamic acid is replaced by valine. D. Lysine is replaced by glutamic acid. (Total 1 mark) 28. What does the karyotype below correspond to? A. A normal male B. A normal female C. A female with Down syndrome D. A male with Down syndrome (Total 1 mark) 36. In some people, hemoglobin always contains the amino acid valine in place of a glutamic acid at one position in the protein. What is the cause of this? A. B. An error in transcription of the hemoglobin gene An error in translation of the mRNA38. The diagram below shows a pair of chromosomes during meiosis in a cell in the human testis. The position of the alleles of some genes is indicated. (a) Deduce, with reasons for your answer, whether the chromosomes are (i) autosomes or sex chromosomes. ............................................................................................................. .............. ............................................................................................................. .............. (1) (ii) homologous or non-homologous. ............................................................................................................. .............. ............................................................................................................. .............. (1) (b) State the stage of meiosis of a cell if it contains pairs of chromosomes as shown in the diagram. ....................................................................................................................... ............... (1) (c) At the end of meiosis, each of the chromatids shown in the diagram will be in a different haploid cell. The diagrams below represent the chromatids inside the haploid cells. Determine the combinations of alleles that would be present on each chromatid. Use the diagrams to indicate your answer. (2) (d) State the pattern of inheritance shown by the three genes. ....................................................................................................................... ............... (1) (Total 6 marks) C. Lack of glutamic acid in the diet D. A base substitution in the hemoglobin gene (Total 1 mark)