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Supplementary Fig. 1 Formation of NPs-PTX, demonstrated by the pale blue color. Supplementary Fig. 2 Intracellular distribution of NPs-PTX-Cou-6 in MCF-7 cells detected by CLSM after 4 h co-incubation. (a-f) Merged images of cellular distribution of NPs-PTX-Cou-6 detected on the z axis of cells from top to down. Cell nucleolus was stained by DAPI (blue), cell cytoplasm was dispersed with NPs-PTX-Cou-6 (green). All scale bars stand for 50 μm.