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8.1-8.2 TAKE DOWN NOTES AND SKETCH MOLECULES DNA was identified as the genetic material through a series of experiments. Griffith used bacteria to find the “transforming principle” that would be identified by Avery as DNA. Deoxyribonucleic Acid– DNA has two strands and is a double helix. Hershey & Chase confirmed that DNA is the material that passes on traits. Epigenetics– our genes can be “tagged” to turn on or off. They can be expressed differently by these tags. We believe epigenetic tags can be controlled by disease, nutrition and lifestyle choice. Chargoff found 4 bases in DNA Adenine ——> Thymine Guanine ——> Cytosine Watson & Crick discovered the double helix shape with help from Rosalind Franklin and Maurice Wilkins *We will go over the movie answers…..just hold onto them. DNA is composed of NUCLEOTIDES that are repeating units….running anti-parallel to each other. The Nitrogenous bases are in two groups: PYRIMIDINES = Single Ring Thymine & Cytosine PURINES = Double Ring Guanine & Adenine Nitrogenous bases are bonded by Hydrogen Bonds Sugars have Covalent bonds to phophates and bases Covalent Covalent Hydrogen Guanine and Cytosine have TRIPLE HYDROGEN bonds Thymine and Adenine have DOUBLE HYDROGEN bonds