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Transcript
BI 102 – General Biology
Instructor: Waite
1
Study Guide for Quiz/Exam 1
Quiz 1: Covers Lectures 1, 2
Exam 1: Covers Lecture 1, 2, 4, 5, Lab 1
Introduction to biology
•
Know the 10 properties or traits that something must display in order to be considered alive
•
Know why a virus is not considered to be alive
•
Define the following terms: metabolism, homeostasis, heritable, adapt, evolve
•
Be able to describe the difference between adapting and evolving
•
Know the 4 classes of biomolecules
Scientific Method
•
Know the 6 steps of the scientific method in order; given a series of steps in solving a problem, be
able to identify the steps of the scientific method
•
Be able to define and differentiate between the following; given examples, be able to identify each
of the following…
•
Hypothesis
•
Theory
•
Scientific theory
•
Law
Water
•
Know why water is so important for life
•
Understand the features of a water molecule that give water its unique properties
•
Understand what a hydrogen bond is
•
Given a diagram of a water molecule, show where the partial charges are; show how one water
molecule interacts with other water molecules through hydrogen bonding
•
Be able to define and differentiate between adhesion and cohesion; know the property of water that
allows it to be both cohesive and adhesive; know the phenomena that result from the interplay
between these forces
•
Know what a surfactant is, and how they work; give examples of surfactants
•
Know the other properties of water that make it so unique
•
Know the definitions of and the difference between the following
•
•
Solute
•
Solvent
•
Solution
•
Solubility
Know the rule of thumb for solubility (“like dissolves like”); be able to determine whether a given
solute is likely to dissolve in a given solvent, given their respective polarities
BI 102 – General Biology
Instructor: Waite
•
2
Study Guide for Quiz/Exam 1
Know the definition of and the difference between hydrophilic and hydrophobic substances, and give
examples of each
•
Know that some substances are both hydrophilic and hydrophobic
END OF MATERIAL FOR QUIZ #1
Cells and Osmosis
•
Be able to describe and differentiate between diffusion and osmosis; know the conditions that must
be present for each to occur
•
Know that when two different substances are present in a concentration gradient, each will diffuse
independently (same direction or opposite direction)
•
Know that some substances can diffuse across cell membranes, and that this requires no energy from
the cell
•
Given a concentration gradient, predict the direction of diffusion relative to the barrier
•
Know the special circumstances that allow osmosis to occur
•
Given a concentration gradient, predict the direction of osmosis relative to the barrier
•
Know that water diffuses in or out of a cell through a membrane protein called aquaporin
•
Know the definition of the term “tonicity,” and the meaning of the following scenarios:
•
•
Hypertonic
•
Isotonic
•
Hypotonic
Given the concentration of a solute both inside and outside a cell, be able to describe the tonicity of
the scenario
•
Given the concentration of a solute both inside and outside a cell, be able to describe the movement
of water in or out of the cell
•
Given the concentration of a solute both inside and outside a cell, be able to describe the result on
the shape of the cell (shrivel, swell/burst, or no change)
Biomolecules
•
Know that all biomolecules are based on carbon-carbon bonds, although they contain other elements
•
Know the 4 categories of biomolecules
•
•
Carbohydrates
•
Lipids
•
Proteins
•
Nucleic acids
Know that all biomolecules are build through polymerization – smaller, fundamental units called
monomers chemically bonded together
•
Know about carbohydrates
•
Also called sugars
•
Monomer = monosaccharides; MANY monosaccharides exist
BI 102 – General Biology
Instructor: Waite
•
3
Study Guide for Quiz/Exam 1
Carbon attached to water (CH2O); given a number of carbons, determine the chemical formula of
a monosaccharide
•
Names end in “-ose”
•
Two monosaccharides linked together = disaccharide; >2 monosaccharides linked together =
polysaccharide
•
Give examples of monosaccharides (e.g. glucose, fructose), disaccharides (e.g. lactose,
sucrose), and polysaccharides (e.g. cellulose, starch, glycogen)
•
Monosaccharides absorbed without digestion; disaccharides and polysaccharides must be broken
down by enzymes; humans lack enzyme required to digest cellulose; what happens if someone
does not make the lactase enzyme?
•
Know that glycogen is the primary short-term energy storage molecule in the body, and why it is
efficient for this purpose
•
•
Know the 5 primary functions of carbohydrates
Know about lipids
•
Fats, waxes, sterols, fat-soluble vitamins (A, D, E, K)
•
No true lipid polymers
•
All hydrophobic
•
Know what makes a fatty acid saturated, monounsaturated, or polyunsaturated; know examples of
where these fats are found; be able to differentiate between these fats given a molecular
diagram
•
Know what a trans fatty acid is, and why they are so problematic
•
Know that triglycerides are the primary long-term energy storage molecule in the body, and why
this is so efficient
•
Know the benefits of fat storage in the body
•
Know that phospholipids are modified triglycerides (one fatty acid replaced with a phosphate
group) and are both hydrophilic and hydrophobic
•
Cholesterol – made by liver in humans; critical cell membrane component; vital to growth and
development, myelin production, and to make steroid hormones (such as estrogen, and
testosterone) and vitamin D
•
•
Know the primary functions of lipids
Know about proteins
•
Monomer = amino acid
•
Know the primary functions of proteins
•
Understand the 4 levels of protein structure; a defect in any level of structure can lead to the
protein functioning poorly or not at all
•
•
Primary – determined by amino acid sequence; depends on peptide bonds (very strong)
•
Secondary – local folding patterns; depends on hydrogen bonds
•
Tertiary – overall 3D folding; depends on hydrogen bonds
•
Quaternary – interaction of two or more fully folded proteins; depends on hydrogen bonds
Know the factors that can disrupt hydrogen bonds (and therefore protein structure)
BI 102 – General Biology
Instructor: Waite
•
4
Study Guide for Quiz/Exam 1
Biological activity of protein highly dependent on shape; changes in shape = denaturation; primary
structure unaffected by denaturation
•
Know about nucleic acids
•
Know the two primary types of nucleic acid
•
Monomer = nucleotide
•
•
Made of phosphate, sugar, nitrogenous base
Understand the structure of nucleic acids – how the nucleotides are attached to each other
(sugar-phosphate backbone), and how the nucleotide bases are positioned
•
Know the primary functions of nucleic acids
•
RNA
•
•
•
Contains bases A, G, C, U
•
Single-stranded
•
3 different types; types coordinate to make proteins based on information coded in DNA
DNA
•
Contains bases A, G, C, T
•
Double-stranded; strands held together by hydrogen bonds
•
Stores all genetic information
Energy carriers
•
ATP = most universal
•
NADH = 7X more energy but not as common
Cells
•
Smallest unit that displays all the characteristics of life
•
Know the elements of cell theory
•
Know the general differences between prokaryotic and eukaryotic cells; give examples of each; given
a diagram, be able to identify each
•
Give examples of unicellular and multicellular eukaryotes
•
Know the 4 basic components all cells have in common and their functions
•
Know the benefit of cells staying small; know why eukaryotic cells are able to grow larger than
prokaryotic cells
•
Know the basic functions of each of the organelles
•
Cell wall (know how this is different from a cell membrane, and which organisms have one)
•
Cytoskeleton
•
Cellular extensions (microvilli, cilia, flagella)
•
Ribosomes
•
Endomembrane system
•
Vacuoles
•
Nucleus
•
Mitochondria
•
Plastids (chloroplasts)