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NUCLEUS AND RIBOSOMES Mary Francis Baxter, Morgan Good, Hannah Moore, Cathie Quamme AP Bio Period 1&2 CHROMATIN Found in eukaryotic plant and animal cells. Located within the nucleus. Is a network of condensed strands - coil into rod-like structures called chromosomes during mitosis May cause ATR-X syndrome - mutations of the ATR-X gene have higher chance of mental retardation, along with facial and skeletal abnormalities Chromatin is similar to a library in that it stores information, and not every chromatin is the same or perfect, just as library books aren’t. NUCLEOLUS Is a structural knot of chromatin. Responsible for the manufacture of ribosomes. Present in eukaryotic plant and animal cells. May cause Parkinson’s disease, a neurological disorder -this occurs when nucleoli do not efficiently carry out protein synthesis, making the cells defective. Is similar to a factory in that both the nucleolus and a factory produce multiples of the same product, being the ribosomes, and also in that both a factory and nucleoli are thrown off in their production greatly when a small malfunction occurs. NUCLEAR PORE •Each cell have multiple pore, each being a pathway for the cell to import and export proteins, and export RNA. •Responsible for the synthesis of RNA . •Found in eukaryotic plant and animal cells. •Can cause various viruses such a HIV -the nucleolus can allow things into the cell whih are harmful, then the nucleus can intensify these. • similar to a river in that different substances flow to a new place, and by it’s path-like structure. CHROMOSOMES •carry genetic info. • equal number of c-somes. •are divded between daughter cells during nuclear division. •contain DNA and some RNA. • found in eukaryotes (animal and plant). • can cause down syndrome among many others. •are much like nurses because they help deliver/care for babies who are basically big bundles of genetic info <3 •AND much like nurses work in hospitals which are like eukaryotic cells because of all their various wards, like a cells organelles. RIBOSOMES •can be found in all prokaryotic and eukaryotic organisms. •are either free-floating in the cytoplasm or attached to the endoplasmic reticulum. •make proteins by connecting amino acids into long chains. •have 2 subunits, which are different for eukaryotic and prokaryotic cells. •are much like construction workers, because they connect the amino acids one at a time and because they build a long chain of them. Some scientists believe that ribosome dysfunction lead to Alzheimer’s disease, Diamond Blackfan Anemia, and gastric cancer C’EST LA FINI!