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Transcript
Module Name
MI4M02
Molecular and Cell Biology
Module Credit Value
10 ECTS
Module Coordinator
Dr. Ursula Bond
Lecturers
Prof. Charles Dorman
Dr. Ursula Bond
Dr. Alastair Fleming
Dr. Kim Roberts
Contact Hours
20 lectures
Recommended Reading List for self guided study
Students will be provided with primary research articles and scientific reviews on specialised
research topics for self-guided study.
Short Content Overview
This module builds on the core concepts of bacterial and eukaryotic gene expression studied in
the Junior Sophister year and introduces students to "up to the minute" developments in
research in this area. Lecture topics include, the dynamic genomes of bacteria and eukaryotic
organisms with an emphasis on yeasts, the compaction and reorganisation of chromatin and
the bacterial nucleoid during gene expression, chromatin modification, biogenesis of RNA,
including RNA polymerase II transcription, RNA processing and export form the nucleus.
Lectures on the interaction of viruses with the host cell machines are provided and students are
introduced to the world of small RNA and the role of small RNAs in viral pathogenesis. Tutorials
on problem solving and data analysis are also provided in this module.