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Blood Cells Flashcards 1. What test measures the percentage of blood volume that consists of erythrocytes by measuring the ratio of packed red blood cells to total blood volume? 2. What is the normal percentage of erythrocytes in blood? 3. Hematocrit measures the percentage of blood volume that consists of what cells? 4. Erythropoiesis is stimulated by what? 5. What is the most abundant type of WBC? 6. What WBC is the first to respond to infection? 7. How do they destroy bacteria? 8. Which WBCs are the ones that primarily destroy the dissolved toxins that bacteria secrete into body fluids? 9. What WBC secretes histamines? 10. What is it called when it leaves the circulation to enter the tissues? 11. Which WBC fights allergies and parasitic infections, and during these conditions, their numbers increase. 12. What are MONOCYTES called when they leave the circulation and enter the tissues? 13. Which WBCs phagocytize bacteria? 14. Do monocytes and neutrophils kill viruses? 15. What WBC kills viruses? 16. What WBC acts against a specific foreign molecule 17. What are the two main classes of lymphocytes? 18. Which WBC attacks organs after an organ transplant? 19. How do B cells fight infection? 20. What are the actual cells that produce the antibodies? 21. What are the two main features of mononucleosis? 22. Which immune system cell type is preferentially destroyed by the AIDS virus? 23. By secreting hormones, the thymus causes which cells to become active? Hematocrit 45% erythrocytes Low oxygen levels NEUTROPHILS NEUTROPHILS Phagocytize bacteria Neutrophils BASOPHILS MAST CELL EOSINOPHILS MACROPHAGES Monocytes (macrophages) and neutrophils. No 1. Lymphocytes (specifically, the Tlymphocytes, also called T-cells) 2. All lymphocytes (B-cells and T-cells) act against a specific foreign molecule. T cells (T-lymphocytes) and B cells (B lymphocytes) T cells by becoming cells that produce antibodies Plasma cells Inflammation of lymph vessels (lymphangitis) Infection of B lymphocytes with the Epstein-Barr virus T cells (T-lymphocytes). T cells (T-lymphocytes). 1 Blood Cells Flashcards 24. Why are most people sick more often as children than as adults in their 20s through 30’s? 25. What is a plasma protein involved in blood clotting? 26. What are platelets responsible for? 27. List the blood cells in order of longevity (life span), from longest—lived to shortest—lived. We build up many varieties of memory lymphocytes during childhood, providing immunity from more and more antigens during adulthood fibrin 28. What is a condition in which the blood’s capacity for carrying oxygen is diminished? 29. What blood disease is a form of anemia where the RBCs have abnormal hemoglobin that deforms the cells into strange shapes (target cells, spheres, but not sickled) 30. Which form of anemia is found especially in the African race; always characterized by sickle-shaped erythrocytes 31. Which form of anemia is from a single amino acid mutation resulting in a valine amino acid substituted for glutamic acid? 32. Which form of anemia is characterized by very large erythrocytes? 33. What type of anemia is from loss of intrinsic factor; a frequent result of gastric bypass surgery? 34. What type of anemia can occur due to a blood transfusion of mismatched blood? 35. What type of anemia is it when a person cannot maintain iron in a reduced state? 36. What type of anemia is from chronic blood loss? 37. What type of disorder of the blood cells causes them to shrink over time due to problems with the red blood cell membrane? 38. What disorder of blood is characterized by too few mature white blood cells? 39. What condition is too few platelets (abnormally low concentration)? 40. What is a hereditary disease of males, where they are unable to clot properly because they are missing some clotting factors? ANEMIA Blood clotting lymphocytes, erythrocytes, platelets, monocytes, neutrophils THALASSEMIA SICKLE CELL DISEASE SICKLE CELL DISEASE Megaloblastic anemia Megaloblastic anemia Acquired Hemolytic anemia G6PD deficiency Hemorrhagic anemia Hereditary spherocytosis LEUKEMIA Thrombocytopenia Hemophilia 2 Blood Cells Flashcards 41. What blood type is the universal donor? 42. What blood type is the universal acceptor? 43. What disorder happens to an RH positive baby of an Rh negative mother? 44. What are the 4 signs of inflammation? 45. How is specific immunity different from nonspecific? 46. What type of immunity is when the body is naturally exposed to an infectious agent and launches an immune reaction? 47. What type of immunity is when a person receives a vaccination? 48. What type of immunity is when a baby receives antibodies through mother’s milk? 49. What type of immunity is when a person receives an infusion of antibodies? 50. What types of allergies are immediate and deadly? 51. What type of allergic response is when the body’s first exposure to the substance will not cause a reaction, but all exposures afterward will trigger the response, such as with poison ivy? 52. What is a hereditary problem where the body thinks its own tissues are foreign bodies, and it constantly tries to kill off its own tissues? 53. What can cause hypoxia (decreased oxygen to the tissues) 54. What is the antidote for arsenic poison (found in rat poison) 55. What is the effect of baby aspirin on prostaglandin synthesis? 56. What does a decrease in PG synthesis do to clotting times? o Type O negative o Type AB positive HDN (Hemolytic Disease of the Newborn) Heat, redness, swelling, pain Non-specific (cell mediated) immune defenses are the monocytes and neutrophils, and also inflammatory responses, physical and chemical barriers. Specific (humoral) immune defenses are from the B cells making antibodies. Naturally acquired active immunity Artificially acquired active immunity Naturally acquired passive Artificially acquired passive immunity Anaphylactic Delayed allergic reaction Autoimmune disease A) Ischemia (reduced blood flow to a tissue) B) Malfunctioning hemoglobin C) Increasing altitude I.v. injection of vitamin K It blocks the ability of COX to cleave arachidonic acid into prostaglandin (decreases PG synthesis) Increases them so it takes longer to form blood clots 3