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Transcript
http://www.unaab.edu.ng 2) Calculate x2 - Draw up a table to show the expected ratios, observed values and calculate the expected values. - Find the difference between each observed and corresponding expected values. - Square the differences. - Divide each squared difference by corresponding expected value. - Sum the resulting quotient to obtain your X2 value. X2 = â (O-E)2 E 3. Inference: The calculated X2 value is compared with Tabulated or Table X2 value at 5% level of significance (95% confidence level) and 3 degrees of freedom (df). Since there are 4 classes phenotypic classes, df = n-1 = 4-1 = 3. Conclusion If calculated X2 is less than tabulated X2 value at 0.05 level of significance and 3 df, accept the null hypothesis and conclude that the two loci are not linked. The genes are indeed located on the same chromosome, F on linkage group I and R on linkage group II. Example 1. Consider a double cross between heterozygous frizzled rose-combed chicken (FfRr) and double recessive normal single-combed individuals (ffrr) which results in 46 offsprings as follows: Frizzled rose FfRr 13 Frizzled single Ffrr 9 Normal rose ffRr 11 Normal single ffrr 13 2 Use X to test if the genes are on separate chromosomes or linked. 25
