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Transcript
DATASOURCES
JANUARY2017
TOTALNUMBEROFINTEGRATEDDATASOURCES:176
TheEuretosKnowledgePlatformisaninnovativebioinformaticsplatformusedby
someoftheworld’slargestpharma&biotechcompanies,academichospitalsand
researchinstitutes.Ouruniqueconfigurabledataloadingplatformenablesusto
updateandextendthecontentoftheplatformefficiently.Asaresult,theEuretos
KnowledgePlatformisthefastestgrowinginterconnectedknowledgebase.
IntheJanuary2017release,theplatformintegratesandinterconnectsdatafrom176sources.These
sourcescanbedividedintwodifferenttypes:
•
LifeSciencesSources–Thesearesourcesthatlifescientistsdirectlyconsultsomeofwhichare
widelyknownsuchasPubmed,Uniprot,Chemblandmanyotherbiologicalsources.
SemanticandOntologicalSources–Thesearesourceslikeontologies,structuredvocabulariesand
thesaurithatareoftennotconsulteddirectlybylifescientistsbutplayacrucialroleinclassifying
lifesciencesdataandrecognizingindividualconcepts.
•
Belowisaselectionfromthesesources.Acompletelistofallsemantic,ontologicalandlifesciences
sourcesisavailabletoourcustomersonrequestwhereweprovidefulldisclosure.
Source
Source
APB
AustralianPhenomeBank
Aracyc
PathwaysinArabidopsisThaliana
ARC
AnimalResourcesCentre
BaselineExpressionAtlas
RNAexpressioninhealthytissue
BIND
Molecularinteractions
BindingDB
Biochemicalinteractiondataforsmallmoleculesandprotein
targets
Biogrid
Protein-proteininteractionsandprotein-smallmolecule
interactions
Biomodels
Computationalmodelsofbiologicalprocesses
BioPlex
Proteininteractionnetworks
CARD
CentreforAnimalResourcesandDevelopment
CellLine
Curatedcelllineoverview
Chebi
Vocabularyforchemicalentitiesofbiologicalinterest
ChEMBL
Compounds,targetsandbiochemicalassays
www.euretos.com
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DATASOURCES
JANUARY2017
ClinicalMeasurementOntology
ClinicalTrials
Clinicaltrials
Clinvar
Clinicalgenomicvariation
CMMR
CanadianMouseMutantRepository
ComparativeToxicogenomics
Database
Gene-phenotype-chemicalinteractions
ConceptWiki
Vocabulary
CORUM
Proteincomplexes
CROP
Geneticannotationsanddiversityoftraitsandenvironmental
treatmentsforplants
DECIPHER
Clinicalphenotypic-genotypicdata
DifferentialExpressionAtlas
Geneexpressionpatternsindifferentbiologicalconditions
DIP
Proteininteractions
DisGeNet
Gene-diseaseassociations
Drugbank
Chemical,pharmacologicalandpharmaceuticalinformationfor
approvedandexperimentaldrugsandproteintherapies
EMMA
EuropeanMouseMutantArchive
EnsemblPlantVariation
(Gramene)
Geneticvariationandphenotypeassociationforplants
Enzyme
Enzymecharacterisation
ExperimentalFactorontology
Ontologyforvariablesinbiologicalexperiments
Fantom5
CAGEexpressiondatainhealthytissue
Foodb
Databaseforfoodandingredients
GeneOntology
Molecularfunctions,biologicalprocessesandcellularcomponents
GTEx
RNA-seqExpressiondatainhealthytissue
GWAS
CuratedresourceofSNP-traitassociations
HGNC
Nomenclatureforhumangenes
www.euretos.com
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DATASOURCES
JANUARY2017
HPRD
Proteininteractionsandpathways
HumanMetabolomedatabase
Smallmoleculemetabolites
HumanPhenotypeOntology
Phenotypicabnormalitiesencounteredinhumandisease
HumanPhenotypeOntology-
Pubmed
DataminingresultsforPhenotype-Diseaseassociations
HumanProteinAtlas
RNAseqandproteinabundancemeasurementinhealthytissues
andcancertissues;Geneclassifications
HumanProteinMap
Proteinabundancemeasurementsinhealthytissues
Humancyc
Molecularpathways
ICD10
Diseaseclassification
INOH
Manuallycuratedpathwaydatabase
Intact
Molecularinteractions
IntActComplex
Proteincomplexes
InternationalMouseStrain
Resource(IMSR)
Mousemodelresources
JAX
Straindatabase
KOMP
KnockoutMouseProject
MeSH
Vocabulary
miRTarBase
MicroRNAtargetinteractions
MMRRC
MutantMouseRegionalResourceCenter
Monarch
Gene-phenotypeassociationsfrommodelorganisms
MonarchCrossSpecies
PhenotypeOntology
Ontology
MouseGenomeInformatics
MGIistheinternationaldatabaseresourceforthelaboratory
mouse,providingintegratedgenetic,genomic,andbiologicaldata
tofacilitatethestudyofhumanhealthanddisease.
MousePhenotypeOntology
Ontology
MRCHarwell
HarwellScienceandInnovationCampus
www.euretos.com
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DATASOURCES
JANUARY2017
MUGEN
MugenMouseDatabase
NationalCancerInstitute
Vocabularyforcancers,agentsandrelatedsubstances
NCBIgeneannotation
Geneinformationandannotation
NCBIgeneorthologues
Geneorthologues
NCBIgenesequence
Referencesequences
NCIPID
Molecularpathways
NCIMR
NationalCancerInstituteatFrederick
Netpath
Manuallycuratedpathwaydatabase
NIG
NationalInstituteofGenetics(Japan)
OMIM
Geneticphenotypes
Orphanet
Rarediseasesandorphandrugs
Panther
Proteinclassifications
Pathwayontology
Classicmetabolic,regulatory,signaling,druganddiseasepathways
PhosphositePlus
Proteinpost-translationalmodifications
Phytozome
Geneorthologsinplants
Plantenvironmentontology
Vocabularyofplantenvironmentalconditionsandexperimental
treatments
Plantontology
Plantanatomy,morphologyandstagesofdevelopmentforall
plants
Pubmed
Scientificliterature;abstracts
RBRC
RikenBioResourceCenter
Reactome
Molecularpathways
ReconX
Humanmetabolism
RxNorm
Drugsvocabulary
SemanticMedline
TextminingresultsofPubmedabstracts
www.euretos.com
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DATASOURCES
JANUARY2017
SGD
GeneticannotationsforSaccharomycescerevisiae
SMPDB
Smallmoleculepathwaydatabase
SNOMEDCT
Clinicalhealthvocabulary
String
Proteininteractions
TAC
TaconicBiosciences
TAIR
GeneticandmolecularbiologyformodelorganismArabidopsis
Thaliana
TheCancerGenomeAtlas(TCGA) RNA-seqExpressiondataincancerpatients
TIGM
TexasA&MInstituteofGenomeMedicine
Traitontology
Vocabularyofplanttraits
TransfacPublic
Generegulation
Uberon
Crossspeciesanatomyontology
UMLS
Biomedicalvocabulary
Uniprot
Proteomics
Vertebratetraitontology
Wikipathways
Manuallycuratedpathwaydatabase
www.euretos.com
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