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Transcript
Introduction
Erik Segerdell
Oregon Health & Science University
RCN Meeting  NESCent  25 February 2011
Xenopus Anatomy Ontology
• XAO describes the anatomy and development of the African
frog Xenopus
• Used to annotate and search for gene expression patterns in
Xenbase (www.xenbase.org)
• OBO Foundry ontology, edited in OBO-Edit
• Anatomical systems, cell and tissue types classified according
to Common Anatomy Reference Ontology (CARO)
• Lineage of tissues represented by develops from relationships,
start and end stages
Xenopus Anatomy Ontology
eagle-i
• Eagle-i: a prototype of a
biomedical research resource
discovery network
• Data model designed in CMAP,
implemented in Protégé
• Re-use/coordination of existing
terminologies
• Upcoming challenges:
enhancement of genotype and
phenotype representation
dx.doi.org/10.1038/npre.2010.5176.1
RCN Ontology Coordination
• Help integrate ontologies at a high level as per the needs of
the working groups and recommendations of the Advisory
Board
• Advise on best practices
• Provide a ‘help desk’ function to new groups who are
developing ontologies
• Help with RCN website administration