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L4: 5-4 Microevolution cont… Variation: differences in species due to mixtures of alleles Variation is inheritable AND due to environmental influences. – Natural selection can only have an effect on the genetic component of variation. Environmental effects: – Hydrangea = blue in acidic soil; pink in alkaline soil – – – – – Flowering time in relation to global climate change Lung cancer due to smoking Gaining weight due to diet Color in flamingos due to diet Siamese cats = darker color in cold weather 1 L4: 5-4 between individuals within a population between populations in different geographical areas polymorphism: subpopulations of different forms – genetic polymorphism = ex. blood types in humans & coat color in Labrador retrievers – phenotypic polymorphism = ex. shells of snail populations Phenotypic polymorphism Genetic polymorphism Types of Selection: Natural selection: some individuals will produce more offspring environment limits population number fitness: relative ability to survive and reproduce; ability to pass genes onto the next generation selection operates on a phenotypic range of variation; not directly on genotype 2 L4: 5-4 disruptive: favors variants at both ends of range; intermediate phenotype is less favorable. stabilizing: trends toward narrow range of phenotype; favors intermediate area of phenotypic range. directional: shifts to variation at edges of variation range; shifts away from average phenotype. 3 L4: 5-4 sexual selection: certain traits lead to preference in mates • Intrasexual selection = within same sex Ex. Male behavior – competition for female • Intersexual selection = mate choice; female choice Ex. Male’s ornaments; eg. Lion’s mane, peacock tail Note: Advantage of passing on genes (getting picked) outweighs the risk of “ornament” increasing chance of predator attack. Examples of Natural Selection peppered moth: black became more prevalent after industrialization - due to soot on trees and - selection against light forms by predators (birds) drug resistance: mutations create enzymes to neutralize antibiotics - antibiotics kill non–mutants but - drug resistant mutants free to multiply - leads to tolerance 4 L4: 5-4 sickle – - cell: recessive hemoglobin gene (afflicts mainly blacks) usually fatal in homozygous recessive condition but heterozygous individuals keep allele in population freq in America: 0.001 freq in central Africa is about 0.045 (heterozygous advantage) - selection advantage for heterozygote to malaria Heterozygous Advantage: Ex. gene that codes for the oxygen carrying protein in blood (hemoglobin) • aa = sickle cell (cannot carry oxygen efficiently or not at all) • Aa = heterozygous advantage - protection against malaria, but not resistant - no sickle cell • AA = very susceptible to malaria / no sickle cell 5 L4: 5-4 Can you see the advantage of the heterozygote? Individuals who are heterozygous at a particular gene locus have greater fitness than the homozygotes. Natural Selection will tend to favor these different alleles ( A and a) at that locus. 6