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Download Single gene disorders
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Transcript
Homozygotes for AD Traits ï Matings that could produce homozygous offspring are rare (A/a x A/a, A/A x A/a or A/A x A/A) ï Disorders are usually more severe in homozygotes ï Example 1: ï¬ ï¬ ï¬ Achondroplasia: a skeletal disorder of short-limb dwarfism and large head size Marriage b/w achondroplastic (heterozygotes) is common Homozygous achondroplastic patients are much more severely affected & commonly do not survive early infancy
