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Divergent evolution: Same basic structure, different appearance, different function, common ancestor Convergent evolution (analogous structure): Evolved independently for similar purposes Parallel evolution: Evolved similar features due to similar environments Taxonomy: Kingdom, phylum, class, order, family, genus, species Species: Individuals have potential to interbreed & produce fertile offspring Microevolution: Changes in allele frequencies/genotypes of population · Genetic Drift: Random changes in certain alleles in small population, reduces genetic variation · Gene flow: Changes the gene pool within each population · Mutations: Changes alleles, alters gene pool, original source of genetic variations · Assortive mating: In breeding, mating with a partner that shares similar phenotypic trait · Natural selection: Unequal success between individuals in producing, fertile offspring. Acts on phenotypes o Stabilising selection: Culls extreme phenotypes o Directional selection: Culls on type of extreme phenotypes o Diversifying selection: Culls intermediate phenotype, leaves extreme o Limits: Historical constraints, role of chance in determining gene pool, can’t create new genes Macroevolution (Speciation) · Formation of a daughter species from a parent species due to changes in allele frequencies · Morphological concept: How they look (physical uniqueness) · Biological concept: Group that is interbreeding & reproductively isolated. Relies on intrinsic factors, temporal/spatial/behavioural isolation, mechanical barriers. Problems: Species that hybridise, asexual species, fossil species · Phylogenetic (molecular) concept: Based on genes/genetic uniqueness · Allopatric: Physical barrier, isolation can be rapid, influenced by differences in environments · Sympatric: Same country, separated by intrinsic factors, populations evolve separately within range of parent species/same environment, behavioural differences Hardy-Weinberg Principle: · Phenotypic frequencies in a population remain constant at equilibrium, p2 + 2pq + q2 = 1 · Assumptions: Individuals mate at random, population is large & stable, no mutation/migration/natural selection Pleiotropy: Multiple effects of single genes, affects more than one trait (eg. colour & stem length) Epistasis: More than one gene acts on characteristic, multiple mutations may not be visible Environment & phenotypes: Gene expression may require certain environmental conditions to become visible Epigenetic Regulation: Outside influences control DNA, X chrom. inactivation (equalises expression of genes in both sexes) Cell Cycle · Interphase: G1 (growth), G0 (99% of cells exit), S (Duplication of homologous pairs), G2 (Growth) · Mitosis: Prophase, Metaphase, Anaphase, Telophase - Diploid cells · Meiosis: Prophase 1, Metaphase 1, Anaphase 1, Telophase 1, Prophase/Metaphase 2, Anaphase 2, Telophase 2 Prokaryotes (Bacteria): · No nucleus, first appeared in fossils 3.5 billion years ago, reproduce asexually, divide every 20 mins · · · · Gram-positive: Thick, multi-layered, dangerous. Gram-negative: Thinner cell walls, respond less to antibiotics, majority 2 kingdoms: Archaea (First ever, analysis of RNA, extreme environments), Bacteria (Common/infections) Functions: Nitrogen cycle, oxygenated the earth, DNA handling techniques Genetic variation: Mutation (resistance), mixing genetic material (transformation, conjunction, transduction) Cell Membrane: Phospholipid molecules, semi-permeable, 2 non-polar tails (hydrophobic), polar head (hydrophilic), moves horizontally, not vertically Properties of water · High surface tension: Water more attracted to itself than other things, H2 bonding/covalent bonding · High specific heat: H2 bonds, takes a lot of energy/heat to break bonds · High heats of vaporisation/condensation: Releases lots of energy as it changes state in opp. direction (latent heat) Biomolecules/macromolecules · Carbohydrates: Carbon chains/rings, lots of OH groups, can occur in linear form, monosaccharide = 1 ring, polysaccharide = chain of rings. Once polys have been built, line them up so they bond to build complex structures · Lipids: Linear chains of carbons, lots of C and H, single bonds = flexibility/saturated, double bonds = unsaturated. · Producing a phospholipid: One tail is replaced by a phosphate group linked to a head, whole molecule becomes amphipathic (polar and non-polar) · Proteins/Polypeptides: Contains N, infinite amount of variants, -COOH and -NH2 present. Limited number that can be built, N-C-C backbone (never changes)