Download Learning your WBC`s

Cell Type
Nucleus
Content
Function
Neutrophil (60%)
3-5 lobes; interconnected
OR Banded (newly
produced)
Specific: anti-bacterial
(smaller/less dense)
Nonspecific: antimicrobial (larger/more
dense)
Glycogen
First to confront bacterial
invasion
Eosinophil (3%)
2-3 lobbed nucleus
Specific granules: large,
anti-parasitic (football
shaped)
Non specific: lysosomal
enzymes
Anti-parasitic and
secondarily recruited to
site of basophilic activity
to counteract
inflammation by basophil
Basophil (1%)
Poorly lobated or Sshaped, basophil nucleus
Basophilic granules
spread throughout entire
cell
Respond to antigenic
stimulation; create
inflammation
Lymphocyte (30%)
Heterochromatin rich
nucleus; thin rim of
basophilic cytoplasm
Few organelles; many free
ribosomes
Monocyte (6%)
Deeply indented or folded
nucleus; lacey chromatin
pattern; substantial
cytoplasm
Abundant organelles;
many lysosomes
Long lived; cellular
immunity (T cells) and
humoral immunity (B
cells)
Precursors for
macrophages
Platelet
Anucleate; biconvex
shaped; derived from
cytoplasm of
megakaryocyte in bone
marrow
Granulomere: central
region with vesicles,
glycogen, lysosomes,
canaliculi, and tubular
elements
Hyalomere: peripheral
region with ring of
microtubules
*Plasma membrane has
dense glycocalyx
Respond to tears in blood
vessels and secrete
factors that promote
platelet aggregation;
catalyze fibrinogen to
fibrin for blood clotting;
PDGF released and actin
and myosin contract clot;
clot is dissolved using
lysosomal granules (more
details pg. 179)