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DNA Replication
Leader:
Course:
Instructor:
Date:
Chelsea
Bio 212(2)
Dr. Vleck
10/2/12
Supplemental Instruction
Iowa State University
Vocabulary:
Antiparallel-Two strands that are parallel but going in different directions.
Semi-conservative- The mechanism which DNA replicate, where the parent strands
separate and serve as a template for the daughter strands, etc.
Complementary- Opposites that combine to form the whole.
Replication fork- Where the unwinding of the helices and new strands are synthesized
occurs.
Telomere- The ends of the chromosome.
Daughter strand-The new strand that is synthesized.
Okazaki fragments- The pieces of the lagging strand.
Primer- Where the DNA Polymerase binds and synthesis starts.
Leading strand- The daughter strand that is made in one piece.
Senescence- The growing old due to deterioration on the molecular level.
Double helix- The structure made from double stranded DNA, due to base stacking.
Parental strand- The template strand for the newly synthesized strand.
What is the function of the following enzymes?
Helicase: Separates the two DNA strands.
Topoisomerase: Alleviates super coiling of the DNA from the Helicase.
Primase: Sets a primer for the daughter strand.
DNA Polymerase III: Synthesizes the new DNA strand.
DNA Polymerase I: Removes the primer and replaces it with DNA.
DNA Ligase: Synthesizes the DNA between the Okazaki fragments.
Telomerase: Adds sequence repeats on the 3’ end, which doesn’t code for anything.
Match the appropriate words (from the vocabulary listed above) to the designated A
through F labels on the diagram.
A=Template/Parental strand. B=Leading strand. C=Lagging strand. D=Replication fork.
E=Primer. F=New/Daughter strand.
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