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Name:_______________________ Date: __________ Pre-Lesson 10: Bacterial Diseases I Pathogenic Gram Positive (+) Bacteria: Many human diseases are caused by Gram+ Bacteria, but we will only discuss some of the families of chapter 19. Staphyloccoccal Infections: Staphylococci are cocci that grow in ____________ like grapes. Although several species can cause disease in this family, two species cause most of the infections in man. The two which cause most of the staph infections are: 1. ____________________ 2. ____________________ _________________________ is a normal part of the skin biota and is found on everyone. It normally does not cause disease. But, it can be an ________________ pathogen when introduced into the body by a puncture or other wound, a medical treatment, or it grows where it should not in an immunocompromised patient, such as with Aids. Mycobacterium: Is a family of Gram+ (positive) bacilli that is unusual because it has ____________________ in its cell wall. This molecule is what kind of a molecule? (protein, carbohydrate, lipid, nucleic acid)__________ . It contains a long chain of 60-90 carbons giving the cells these properties: a _________ growth rate (it takes time to make the long chain of carbons for the lipid), protection from _______________________ by macrophages and other leukocytes, growth with in ___________ including macrophages, resistance to __________, Mycolic acid allows the cell to retain water and survive for months, ________________ to detergents, many antibiotics, and other water based or water soluble agents, resistance to Gram staining, the lipid cell wall does not stain well (the Gram stains are water soluble). The cells have _________________ staining properties (unlike other cells, the lipid cell walls readily take up acid fast stains (acid fast stains are non-polar). The cell membrane and the outer membrane of the cell wall of Gram- (negative) cells have lipids but do NOT take up and retain acid fast stains. Briefly, explain why this might be? _______________________________________________________________________________________________ _______________________________________________________________________________________________ Species of Mycobacterium: There are around 75 species known in the family, but only 3-4 species (depending on your edition) cause disease in man: Species: Disease: