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Transcript
FOUNDATION MODULE 2012
SELF ASSESMENT BCQs
6TH WEEK
(DEVELOPMENT AND GENETICS)
Q1)Regarding transcription following is incorrect?
d) It is a process of formation of DNA from
RNA**
Q2)Which of the following is not the function of sympathetic nervous system?
c)Pupils are constricted. ***
Q3)Which of the following neurotransmitter is released by preganglionic axons?
c)Acetylcholine. ***
Q4)Nucleotide triphosphtes required for transcription are:
e)All***
Q5)Cranial outflow does not consist of the following nerve?
c) Vestibulocochlear nerve (VIII). ***
Q6)Gastrulation is characterized by
a) Formation of mesoderm. ***
Q7)Following are the requirements for transcription except
d)DNA polymerase**
Q8)Which of the following regarding parasympathetic nervous system is not
true?
e)The vasodilator fibres release epinephrine and
norepinephrine.***
Q9)First sign of gastrulation is the formation of
c) Primitive streak. ***
Q10)Regarding post transcriptional modification of RNA incorrect is
d) Eukaryotic mRNA is generally identical to its primary
transcripts**
Q11)Regarding the parasympathetic division of the autonomic nervous system,
select the CORRECT statement:
d) Parasympathetic postganglionic fibers secrete
acetylcholine onto their target organs. ***
Q12)The prechordal plate is the primordium of
e)Oral cavity. ***
Q13)Which of the following is TRUE of the sympathetic nervous system?
c) It uses different neurotransmitters at the
ganglion and at the synaptic cleft. ***
Q14) Microsomal oxidation of Phase I Reactions include :
e) Salicylates. *****
Q15)In Eukaryotic mRNA following is not correct
b) Introns are the coding regions**
Q16)Regarding genetic code:
c) Methionine and tryptophan have only 1
codon***
Q17)Which statement is odd regarding Somites
e) Square in shape on transverse section. ***
Q18) Phase II reaction of drug metabolism includes:
d) Conjugation *****
Q19)Neurulation involves formation of the :
e) Neural tube.***
.
Q20) Which is the major organ for the
biotransformation of drugs?
c) Liver. *****
Q21)Neural crest cells give rise to the following except:
e) The suprarenal(adrenal cortex)***
Q22)Regarding initiation:
c) Initiator factors facilitate the assembly of this
initiation complex***
Q23)Ability of a drug to bind a receptor is called?
e)Affinity***
Q24)Regarding acetylcholine:
a. Binds with nicotinic receptors causing ionotropic effect***
Q25) Colchicine has receptor?
b) Tubulin.***
Q26)Many metabolites of drugs created in the liver are excreted into the
intestinal tract in?
d) bile. ***
Q27) In conservative theories of replication.
b) One new strand is formed.***
Q28)Substances excreted in the feces usually involve orally ingested unabsorbed
drugs or metabolites excreted in the bile that are not reabsorbed from the
intestinal tract?
d) intestinal tract***
Q29)Regarding epinephrine and nor epinephrine:
b. Beta-blockers block beta receptors causing
decrease in heart rate***
Q30)Receptors linked via G- proteins are typically?
c) 7 transmembrane spanning domains.***
Q31) cGMP is a second messenger in?
b)Vascular smooth muscle***
Q32) Regarding parasympathetic activation:
d. Parasympathetic fibers cause vasodilation and
are responsible for erection of the penis and
cilitoris ***
Q33) Ability of drug to produce pharmacological effect after binding to a
receptor is called?
b)Intrinsic ability.***
Q34)Organs that excrete drugs eliminate polar compounds (water soluble) more
readily than components with high?
a)Lipid solubility.**
Q35)GABA receptor in the which is coupled to a chloride ion channel, can be
modulated by anticonvulsants, benzodiazepines and barbiturates.?
d)CNS**
Q36)Regarding Sympathetic role:
b) Stimulates the reticular activating system of
the brain causing increased mental alertness***
Q37) Regarding Telomerase.
d) Non- Coding sequence of DNA complex with
proteins.***
Q38) In DNA polymerases function of POL α is
a) Initiates DNA synthesis.***
Q39) Coffin-Lowry syndrome is caused by mutation in
a) Ribosomal protein gene***
Q40)Changes in genomic sequence is termed as:
d) Mutations.***
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