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Drag and Drop Protein Synthesis Name Period Type in the following address in the menu bar http://www.zerobio.com/drag_oa/protein/overview.htm You will be completing the transcription and translation activity by dragging and dropping the correct bases to practice the process of protein synthesis. TRANSCRIPTION Click on the transcription tab Read the introductory information on this process WHAT DOES THE SEQUENCE OF DNA THAT YOU ARE ABOUT TO TRANSCRIBE REPRESENT? T Complete the transcription of the DNA sequence that is given to you List the m-RNA strand that you transcribed from the DNA sequence Answer the questions below about your results and check your answers. Write your answers below QUESTIONS Which base in RNA is replaced by uracil? How many mRNA codons are illustrated above? What is the name of the enzyme that creates the mRNA copy from DNA? What is the name of the sugar in the mRNA nucleotides? What is the mRNA transcript for the DNA sequence, TTACGC Click Next on the lower right hand corner TRANSLATION Read the information on translation to review this process Complete the translation of the m-RNA sequence by dragging and dropping the correct bases in order QUESTIONS What organelle assists tRNA in translating the mRNA in the cytoplasm? The role of tRNA is to carry a(n): Is a tRNA anticodon more similar to DNA or RNA in nucleotide sequence? If the mRNA codon is CGA, the tRNA anticodon that binds with it is: Click Next on the lower right hand corner Protein Synthesis 1 Activity: Complete the activity and write your responses in the template below QUESTIONS 1-How many amino acids are coded for by the DNA? 2-What protein does this DNA code for? 3-If instead of ACT, the first DNA triplet was ACG, which amino acid would be coded for? 4-What amino acid is carried by a tRNA with the anticodon, GUA? 5-Sickle cell anemia is a disease of red blood cells in which a genetic mutation in DNA leads to a mutation in hemoglobin. A single base change alters the DNA sequence CTC to CAC which codes for the wrong amino acid. What amino acid is coded for by the normal DNA sequence, CTC? 6-For the question above, what amino acid is coded for by the mutated DNA sequence, CAC? Click Next on the lower right hand corner to take the interactive quiz and write the correct answers below 1.Transcription is the first step of Protein Synthesis and it occurs in the: 2. Translation is the second step of Protein Synthesis and it occurs in the: 3. If a DNA sequence consists of 12 nucleotides, how many mRNA codons will there be? 4. The enzyme that creates mRNA from a DNA sequence is called: 5. Each codon of mRNA (hence each triplet in DNA) codes for one: 6. The specific amino acid carried by a tRNA is determined it's: 7. True or False? When amino acids are brought in by tRNA, they are joined together by hydrolysis reactions to form the growing protein. 8. True or False? Whenever a cell needs to, it can unzip DNA and make a transcript of a sequence so that a protein can be made. DNA then zips up. 9. True or False? The same amino acid can be carried by different tRNA'S. 10. Although not discussed in this activity, Translation actually takes place in 3 steps: