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AP Biology Study Guide Chapter 9b: Patterns of Inheritance (9.11-23 Chromosomal Inheritance) Variations on Mendel’s Laws Describe the inheritance patterns of incomplete dominance, multiple alleles, codominance, pleiotropy, and polygenic inheritance. Provide an example of each. Explain how the sickle-cell allele can be adaptive. Explain why human skin coloration is not sufficiently explained by polygenic inheritance. The Chromosomal Basis of Inheritance Define the chromosome theory of inheritance. Explain the chromosomal basis of the laws of segregation and independent assortment. Explain how linked genes are inherited differently from nonlinked genes. Describe T. H. Morgan’s studies of crossing over in fruit flies. Explain how crossing over produces new combinations of alleles. Explain how Sturtevant created gene maps. Sex Chromosomes and Sex-Linked Genes Explain how sex is genetically determined in humans and the significance of the SRY gene. Compare the sex determination system in humans to those in fruit flies, grasshoppers, birds, and bees. Describe patterns of sex-linked inheritance, noting examples in fruit flies and humans. Explain why sex-linked disorders are expressed much more frequently in men than in women. Explain how the Y chromosome can be used to trace human ancestry. C. Gay 10/8/08 Steamboat Springs High School AP Biology Key Terms ABO blood groups chromosome theory of inheritance codominant complete dominance Duchenne muscular dystrophy hemophilia incomplete dominance linked genes pleiotropy polygenic inheritance recombinationfrequency red-green colorblindness sex chromosome sex-linked gene C. Gay 10/8/08 Steamboat Springs High School AP Biology