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Mendel/Genetics Enduring Understandings • The work of Gregor Mendel describes the basis by which traits, coded for by genetic information, are passed from one generation to the next. Essential Questions • How is heritable information passed from one generation to the next? • What are different patterns by which heritable information passed from one generation to the next? • How does this unit provide evidence of the relatedness of living things in the world? Targets Vocabulary—Heredity, genetics, pea plants, monohybrid cross, true-breeding/purebreeding, P generation, F1 generation, F2 generation, alleles, dominant, recessive, homozygous, heterozygous, genotype, phenotype, law of segregation, law of independent assortment, punnett square, dihybrid cross, pedigree, sex-linked (x linked/xy inheritance), polygenic inheritance, incomplete dominance, codominance, multiple alleles, autosomal inheritance, sickle cell anemia, cystic fibrosis, hemophilia, huntington’s disease • • • • • Be able to discuss the genotypes and phenotypes of Mendel's P, F1 and F2 generations and be able to carry out these crosses. Know Mendel's Law of Segregation and Law of Independent Assortment and illustrate these laws in an appropriate cross. Be able to carry out crosses concerning complete dominance, incomplete dominance, co-dominance, sex-linked inheritance, multiple alleles, and dihybrid crosses in addition to understanding polygenic inheritance. Be able to interpret pedigrees. Be able to identify and distinguish between the following autosomal genetic diseases: sickle cell anemia, cystic fibrosis, hemophilia, huntington’s disease