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C- 5 DNA & Modern Genetics - Vocabulary List Section 5.1 1. DNA – (pg 74) = Code. The genetic material found in all living cells that contains the information needed for an organism to grow, maintain itself, and reproduce. Deoxyribonucleic acid A = T C = G 2. protein – (pg 43) one of many types of molecules made up of chains of amino acid subunits. Proteins control the chemical activity of a cell and support growth and repair. o-o-o-o-o-o-o-o enzymes made of proteins. 3. amino acids – (pg 43) subunits that make up proteins. Looks like a string of pearls. 4. nucleotides – (pg 44) subunits of nucleic acid. Makes up DNA and RNA. Looks like a house (sugar) with 1 or 2 car garage (nitrogen containing bases) and a lollypop fireplace (phosphate group). 5. replication – (pg 137) the process by which DNA is copied before it condenses into chromosomes. It happens during interphase in the nucleus. 6. template – (pg 138) A mold. Hand in plaster. Stand of DNA used as a template to reproduce a copy of the other strand. 7. RNA (3 types) - (pg 138) include functions – A molecule that carries genetic information from DNA (the code) to a ribosome, where the genetic information is used to form a protein. *mRNA (the codon) gets the code from DNA and carries it to a ribosome. Can travel from the nucleus to the cytoplasm. mRNA contains the codon and is complementary to the one side of the DNA molecule. *rRNA or ribosomal RNA makes up ribosomes, the site of protein synthesis. *tRNA or transfer RNA (the anitcodon) is complementary to mRNA (the codon) and brings amino acids to the site on the ribosome for protein synthesis. 8. transcription – (pg 138) the process of transferring information from DNA (the code) to mRNA (the codon). This process happens in the nucleus. 9. translation – (pg 139) mRNA codon to tRNA anticodon. Forms a protein in the cytoplasm on a ribosome. 10. base – (pg 136) part of a nucleotide. DNA contains 4 types: A = T and C= G. RNA contains 4 types A= U and C = G. 11. triplet – (pg 137) the genetic code is a triplet code, a sequence of 3 nucleotide bases that code for one amino acid. T-C-T codes for the amino acid arginine. 12. complimentary – (pg 138) matching A and G are purines = double ringed bases (a 2 car garage) C and T are pyrimdines = single ringed base (a 1 car garage) Section 5.2 13. mutation – (pg 145) any change made to DNA. 14. genetic disorder – (pg 146) disease or condition that results from mutations that affect the normal function of a cell. 15. cancer – (pg 158) a group of disorders characterized by the uncontrolled division of cells. Known as “selfish cells” that divide indefinitely and are considered immortal. 16. pedigree – (pg 147) a chart that shows family relationships including 2 or more generations. 17. carcinogen (pg 148) cancer causing harmful chemicals. Nicotine and ultraviolet light. Section 5.3 18. selective breeding – the process of selecting and breeding parent organisms to pass on particular traits of offspring. (dogs) 19. genetic engineering – (pg 151) the scientific process in which DNA is separated from an organism, changed, and then re-inserted into the same or different organism. 20. genetic modified (GM or transgenetic) – using technology, scientists can take a gene from one species and transfer it into the DNA of an organism from another species. 21. DNA fingerprint – (pg 153) a DNA profile of about 10 regions to specify whom a sample belongs to (unless there is an identical twin). 22. human genome project – sequencing the 3 billion nucleotide pairs in a single set of human chromosomes. Huge project. MIT and private sector scientific corporations involved. 23. genome – (pg 154) all of the DNA of an organism including its genes. The genetic material of an organism. 24. cloning - (pg 154) the process of using DNA technology to create an offspring that is genetically identical to its parent. 25. Dolly – first mammal cloned (a sheep). Read all about Dolly in section 5.3.