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Study Guide for CCP Biology TEST: Chapter 14 + 15 This test will consist of several sections. Some will be multiple choice and some parts you will have to fill in short answers. There will also be diagrams and a pedigree to interpret. Chapter 14: Human Heredity You should be able to: Define: karyotype, autosome, nondisjunction, pedigree, carrier, gene therapy. Interpret a pedigree chart (sex, genotype, phenotype and relationships represented by symbols) Recognize the patterns of three common modes of inheritance—autosomal dominance, autosomal recessive and sex-linked recessive—on a pedigree chart. Describe the inheritance of blood type in humans, including what is physically different on the blood cells with various allele combinations. Describe the possible outcome of nondisjunction in autosomes and sex chromosomes. Explain why most harmful genetic disorders are inherited through recessive alleles. Identify the heredity and symptoms for common human genetic disorders such as Tay-Sachs, hemophilia, Cystic Fibrosis, Huntington’s disease and color blindness. Chapter 15: Genetic Engineering You should be able to: Define or explain the following terms: selective breeding, inbreeding, genetic engineering, recombinant DNA, restriction enzyme, sticky end, and clone. Describe the action of restriction enzymes and their uses. Define a transgenic organism and explain the purpose of producing them. Describe the basic process of cloning animals (i.e. the source of the DNA and the resulting genetic make-up of the clone).