* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Review_Pedigree ans
Gene therapy of the human retina wikipedia , lookup
Microevolution wikipedia , lookup
Gene expression programming wikipedia , lookup
Artificial gene synthesis wikipedia , lookup
Tay–Sachs disease wikipedia , lookup
Biology and consumer behaviour wikipedia , lookup
Skewed X-inactivation wikipedia , lookup
Y chromosome wikipedia , lookup
Saethre–Chotzen syndrome wikipedia , lookup
Quantitative trait locus wikipedia , lookup
Dominance (genetics) wikipedia , lookup
Neocentromere wikipedia , lookup
Fetal origins hypothesis wikipedia , lookup
Public health genomics wikipedia , lookup
Epigenetics of neurodegenerative diseases wikipedia , lookup
Neuronal ceroid lipofuscinosis wikipedia , lookup
X-inactivation wikipedia , lookup
Pedigree Worksheet I 1 II 1 2 2 4 = Huntington’s Disease 5 3 6 7 8 III 1 2 3 4 5 1. Which members of the family above are afflicted with Huntington’s Disease? I-1, II-2, II-3, II-7, III-3 2. There are no carriers for Huntington’s Disease- you either have it or you don’t. With this in mind, is Huntington’s disease caused by a dominant or recessive trait? Dominant 3. How many children did individuals I-1 and I-2 have? 6 4. How many girls did II-1 and II-2 have? 5. How is individual III-2 and II-4 related? How many have Huntington’s Disease? 2 Uncle/Niece 6. The pedigree to the right shows the passing on of Hitchhiker’s Thumb in a family. Is this trait dominant or recessive? recessive I 7. How do you know? III-1 and III-2 must have the gene in order to have affected children, but do not show the trait. 8. How are individuals III-1 and III-2 related? First Cousins II I-2 and III-5? 1 Grandmother/grandson 1 2 1 2 3 4 1 III 2 3 4 IV 9. Name 2 individuals that have hitchhiker’s thumb. IV-1, IV-3 1 2 3 10. Name 2 individuals that were carriers of hitchhiker’s thumb. III-1, III-2 11. Is it possible for individual IV-2 to be a carrier? to be Hh also (punnett square) Yes Why? Since her parents were Hh, she has a 50% chance 12. The pedigree to the right shows the passing on of colorblindness. What sex can ONLY be carriers of colorblindness? Female I 13. With this in mind, what kind of non-mendelian trait is colorblindness? Sex-linked II 14. Why does individual IV-7 have colorblindness? The individual received an affected X chromosome from mother and father. III 15. Why do all the daughters in generation II carry the colorblind gene? Dad’s X chromosome has the affected gene. Since daughter received an X chromosome from the mother and the father, one of their X chromosomes is also affected. 16. Name 2 IV generation colorblind males. IV-1, IV-5 IV 1 2 3 4 5 6 7