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Name ______________________________________Block _______ Date ________________ Pedigree Problem Set I II 1 2 1 2 4 5 = Huntington’s Disease 3 6 7 8 III 1 2 3 4 5 1. Which members of the family above are afflicted with Huntington’s Disease? ____________________________ 2. There are no carriers for Huntington’s Disease- you either have it or you don’t. With this in mind, is Huntington’s disease caused by a dominant or recessive trait? ___________________ 3. How many children did individuals I-1 and I-2 have? _______________________________________________ 4. How many girls did II-1 and II-2 have? ___________ How many have Huntington’s Disease? _______________ 5. How is individual III-2 and II-4 related? _____________________ I-2 and III-5? _______________________ 6. The pedigree to the right shows the passing on of Hitchhiker’s Thumb in a family. Is this trait dominant or recessive? ____________________ I 8 1 2 1 2 7. How do you know? ______________________ II 8. How are individuals III-1 and III-2 related? ________________________ 9. Name 2 individuals that have hitchhiker’s thumb. __________________ II I 3 1 4 2 3 IV 1 10. Name 2 individuals that were carriers of hitchhiker’s thumb. ______________ 2 3 I 11. Is it possible for individual IV-2 to be a carrier? __________ Why? __________________________________ 12. The pedigree to the right shows the passing on of colorblindness. What sex can ONLY be carriers of colorblindness? __________________________ 13. With this in mind, what kind of non-mendelian trait is colorblindness? ______________________ 14. Why does individual IV-7 have colorblindness? __________________________________________ II II I IV 1 2 3 4 5 6 7 4 15. Why do all the daughters in generation II carry the colorblind gene? _________________________ 16. Name 2 IV generation colorblind males. _________ 17. Below is a pedigree of the Brown family. The shaded individuals are color blind. Color blindness is a sexlinked, recessive trait. Fill in the genotype of as many individuals as you can. 18. Construct a pedigree with the following information, and answer the questions at the end. You should considered brown hair to be dominant and blonde hair to be recessive. (It is really more complicated than this!) You should shade in those individuals in the pedigree who have blond hair. Be sure to show all genotypes. Generation I: A man with brown hair marries a woman with blonde hair who is one year older than the man. Generation II: They have 5 children. The first-born is a girl, who marries a man with blonde hair. The second and third born are boys with blonde hair. The fourth and fifth born were girls, both with brown hair. The youngest daughter marries a man with brown hair. Generation III: The marriage of the oldest daughter from generation II produces 3 girls, all of whom have blonde hair. The marriage of the youngest daughter from generation II produces 2 boys that are identical twins, both have blonde hair. Is it possible for the children in generation 3 to have brown hair? Label the pedigree with as many genotypes as you can.