* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Document
Gluten immunochemistry wikipedia , lookup
Complement system wikipedia , lookup
Molecular mimicry wikipedia , lookup
DNA vaccination wikipedia , lookup
Vaccination wikipedia , lookup
Lymphopoiesis wikipedia , lookup
Monoclonal antibody wikipedia , lookup
Sjögren syndrome wikipedia , lookup
Hygiene hypothesis wikipedia , lookup
Immunocontraception wikipedia , lookup
Adoptive cell transfer wikipedia , lookup
Immune system wikipedia , lookup
Polyclonal B cell response wikipedia , lookup
Cancer immunotherapy wikipedia , lookup
Adaptive immune system wikipedia , lookup
Herd immunity wikipedia , lookup
Social immunity wikipedia , lookup
Innate immune system wikipedia , lookup
CHAPTER 13: THE LYMPHATIC SYSTEM AND IMMUNITY A&P II HS130 Professor Tracy Abram, MAIS, BS Objectives • Function of Lymphatic System • Discuss primary lymphatic structures • Compare nonspecific and specific immunity • Compare active and passive immunity • Immune system • Function of B and T Cells Lymphatic and Immune These systems work together to defend our body and maintain Homeostasis! What do you know about Lymph? • Clear fluid: enters through left and right subclavian veins • Collects between cells throughout body • Active part of Lymphatic system • Passive movement in lymph vessels via muscle contraction How is lymph formed? http://www.lymphnotes.com/article.php/id/1 51/ Lymph fluid • Formed from blood plasma • Blood plasma filters out of capillaries • Between tissue cells • Also known as tissue fluid or interstitial fluid • ***Circulatory system plays a starring role in assisting the • Lymphatic system Figure 13-3 page 340 Right Lymphatic Duct • Responsible for lymph drainage from right upper extremity, right side of head, neck, and upper torso Thoracic Duct • Largest lymphatic vessel • Contains pouch: cisterna chyli (see figure 13-1 page 338) • Drains lymph from about 75% of the body Lymph Nodes Primary function: Defense and WBC producer Clusters that vary in size along lymphatic vessel Professor Abram’s Scenario Time! • Artemio, Mary, Veronica, and Nikita go to this fancy, virtual restaurant for dinner. Everyone orders their food: chicken wings, sushi, rice, seaweed salad, peas and carrots, steak, and salad. They are having a marvelous time discussing A&P II when Artemio suddenly gets sick and runs to the restroom (diarrhea). • What do you think happened to Artemio? Thymus Endocrine gland and Lymphoid Tissue Organ Produces T-cells (Tlymphocytes) Secretes thymosin (hormone) Vital to Immune Response PubMed. Immunol Rev. 2002 Jul;185:7-14. The discovery of thymus function and of thymusderived lymphocytes. http://www.ncbi.nlm.nih.gov/ pubmed/12190917 • http://www.webmd.com/oralTonsils Made of 3 masses of lymphoid issue around opening of mouth and throat Three types of tonsils: • Palatine- “tonsils” • Pharyngealadenoids • Lingual health/picthttp://www.webmd. com/oral-health/picture-ofthhttp://www.webmd.com/oral -health/picture-of-thetonsilse-tonsilsure-of-thetonsils Spleen Largest Lymphatic Organ Location: Upper left quadrant of abdominal area Functions: Phagocytosis of bacteria and “old junkyard” for RBCs Immune System • What do you know about the Immune System? Answer: Immune System • Protects body from bacteria, foreign tissue cells, and cancerous cells • Made of groups of organs, cells, and molecules • Let’s discuss the different types…shall we? Nonspecific vs Specific Immunity • Nonspecific • Specific • Innate immunity • Adaptive Immunity • Skin • Two types: Natural and • Tears and mucus • Inflammation (figure 13-8 page 344) Artificial Immunity INNATE AND NON-SPECIFIC IMMUNITY Khanacademy.org. (2010, February 18). Role of Phagocytes in Innate and Nonspecific immunity. [YouTube].Retrieved from http://www.youtube.com/watch?v=O1N2rENX q_Y Natural Immunity • Active: • active disease produces immunity • **not deliberate • Passive • Immunity passed from mother to fetus via placenta or breast milk Artificial Immunity • Active • Passive • Vaccination results in • Protection developed immunity • ***deliberate exposure in another individual’s immune system and given to non-immune person Immune System Molecules • What are antibodies? • What is humoral or antibody-mediated complex? • Figure 13-9 page 346 • How do Complement Proteins work? • Figure 13-10 Let’s Play the Matching Game! • 1. lymphocytes • 2. Kupffer’s cells • 3. Monocyte • 4. Neutrophil • 5. B lymphocyte • 6. T lymphocyte • 7. Thymus • 8. Spleen • 9. Lymph • 10. Lymph nodes a. Numerous cells of immune system b. Immune defense c. liver macrophage d. secrete antibodies e. Most numerous granulytes f. does not secrete antibodies, but attacks bacteria g. plasma fluid h. WBC formation and defense i. Junkyard for RBCs j. endocrine gland