Download INTEGUMENTARY SYSTEM - Coast Colleges Home Page

LYMPHATIC SYSTEM
LYMPHATIC SYSTEM
FUNCTIONS
Return Tissue Fluid (Lymph) to Blood
(Lost from Blood Capillaries)
Defend Against Disease
- Production & Differentiation of
Lymphocytes
- Develop Antibodies
Transport Fats from Digestive Organs to
Blood
LYMPHATIC SYTEM
COMPONENTS
Lymph
- Fluid, Similar to Plasma
- Lost from Blood Capillaries
- Returned from Interstitial Spaces to Blood by
Lymph Vessels (Lymphatics)
- Transport Lymph (one-way) to Blood
(Subclavian Veins)
Lymph Vessels continued
- Begin as Blind-ended Capillaries in Interstitial
Spaces
- Contain One-way Valves
- Cisterna Chyli (from Digestive Organs, pools
at L-2, Drains superiorly into:
- Thoracic Duct (Drains Lower Body + Upper
Lt. Half into Lt. Subclavian Vein)
- Right Lymphatic Duct (Drains Upper Rt.
Half into Rt. Subclavian Vein)
COMPONENTS continued
Lymphatic Organs & Tissues:
- Lymph Nodes
* Located Along Lymph Vessels
* Filter Lymph (Macrophages &
Lymphocytes)
* Occur in Clusters (Cervical, Axillary,
Inguinal, etc.)
- Thymus
* Major Site of T Cell Maturation
COMPONENTS continued
- Spleen
* Filters Blood (Lymphocytes &
Macrophages)
* Recycles RBCs & Stores Iron
* Blood Reservoir
- Bone Marrow
* Origin of Immature Lymphocytes
COMPONENTS continued
- M.A.L.T. (mucosa-associated lymphatic
tissue)
* Nodules in mucous membranes
* G.I., urinary, reproductive tracts &
respiratory airways
* Includes;
Peyer’s Patches in intestines
Tonsils in Pharynx
Immune System
Non-Specific/Innate Defenses
Barriers – skin, mucous membranes, tears
Phagocytes – Neutrophils, Macrophages
Natural Killer Cells – lymphocytes that
lyse/kill cancer cells & virus-infected cells
Proteins – complement & interferon
Inflammation – Redness, Heat, Pain,
Swelling
Fever
Specific/Adaptive Defenses
Antigen-specific (relies on recognition of
foreign antigens)
Systemic (body-wide)
Memory (stronger future immune response)
2 types of Immune Response:
- Humoral (Antibody-Mediated)
- Cellular (Cell-Mediated)
Humoral Immunity
B Cells (B-Lymphocytes)
- Mature in Bone Marrow
- Protect against Bacteria, Foreign
Proteins, Viruses
- Divide to form:
* Plasma Cells (Produce Antibodies)
* Memory B Cells
Cellular Immunity
T Cells (T-lymphocytes)
- Mature in thymus
- Influence B-cells
- Protect against Viruses & Cancer