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PowerPoint® Lecture Slides prepared by Janice Meeking, Mount Royal College CHAPTER 13 The Peripheral Nervous System and Reflex Activity: Part A Copyright © 2010 Pearson Education, Inc. Peripheral Nervous System (PNS) • All neural structures outside the brain • Sensory receptors • Peripheral nerves and associated ganglia • Motor endings Copyright © 2010 Pearson Education, Inc. Central nervous system (CNS) Peripheral nervous system (PNS) Sensory (afferent) division Copyright © 2010 Pearson Education, Inc. Motor (efferent) division Somatic nervous system Autonomic nervous system (ANS) Sympathetic division Parasympathetic division Figure 13.1 From Sensation to Perception • Survival depends upon sensation and perception • Sensation: the awareness of changes in the internal and external environment • Perception: the conscious interpretation of those stimuli Copyright © 2010 Pearson Education, Inc. Sensory Integration • Input comes from exteroceptors, proprioceptors, and interoceptors • Input is relayed toward the head, but is processed along the way Copyright © 2010 Pearson Education, Inc. Perceptual level (processing in cortical sensory centers) 3 Motor cortex Somatosensory cortex Thalamus Reticular formation Pons 2 Circuit level (processing in Spinal ascending pathways) cord Cerebellum Medulla Free nerve endings (pain, cold, warmth) Muscle spindle Receptor level (sensory reception Joint and transmission kinesthetic to CNS) receptor 1 Copyright © 2010 Pearson Education, Inc. Figure 13.2 Perceptual level (processing in cortical sensory centers) 3 Motor cortex Somatosensory cortex Thalamus Reticular formation Pons 2 Circuit level (processing in Spinal ascending pathways) cord Cerebellum Medulla Free nerve endings (pain, cold, warmth) Muscle spindle Receptor level (sensory reception Joint and transmission kinesthetic to CNS) receptor 1 Copyright © 2010 Pearson Education, Inc. Figure 13.2 Structure of a Nerve • Cordlike organ of the PNS • Bundle of myelinated and unmyelinated peripheral axons enclosed by connective tissue Copyright © 2010 Pearson Education, Inc. Structure of a Nerve • Connective tissue coverings include: • Endoneurium—loose connective tissue that encloses axons and their myelin sheaths • Perineurium—coarse connective tissue that bundles fibers into fascicles • Epineurium—tough fibrous sheath around a nerve Copyright © 2010 Pearson Education, Inc. Endoneurium Axon Myelin sheath Perineurium Epineurium Fascicle Blood vessels (b) Copyright © 2010 Pearson Education, Inc. Figure 13.3b Regeneration of Nerve Fibers • Mature neurons are amitotic • If the soma of a damaged nerve is intact, axon will regenerate Copyright © 2010 Pearson Education, Inc. Endoneurium Schwann cells Droplets of myelin 1 The axon becomes fragmented at the injury site. Fragmented axon Site of nerve damage Copyright © 2010 Pearson Education, Inc. Figure 13.4 (1 of 4) Schwann cell Copyright © 2010 Pearson Education, Inc. Macrophage 2 Macrophages clean out the dead axon distal to the injury. Figure 13.4 (2 of 4) Aligning Schwann cells form regeneration tube 3 Axon sprouts, or filaments, grow through a regeneration tube formed by Schwann cells. Fine axon sprouts or filaments Copyright © 2010 Pearson Education, Inc. Figure 13.4 (3 of 4) Schwann cell Site of new myelin sheath formation 4 The axon regenerates and a new myelin sheath forms. Single enlarging axon filament Copyright © 2010 Pearson Education, Inc. Figure 13.4 (4 of 4)