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(11) Cloning 6.9 (194) Reproduction in Flowering Plants (7.3) 208 BLM 7.3a & b http://morgan.rutgers.edu/morganwebfra mes/level1/page2/ChromNum.html Cloning Cloning is the process of forming identical genetic offspring from a single cell. It is a natural process that happens daily in nature when organisms produce exact duplicates of themselves by asexual reproduction (binary fission, budding…). Cloning is referred to as asexual reproduction because the DNA originates from a single parent. The First Clone Cloning started in 1958 when Frederic Stewart grew a carrot from root cells. Clones are not actually identical in appearance; rather they are identical in genetics. Remember: A clone has the genes of only 1 parent so it is genetically identical to that parent. (We have ½ our genes from one parent and ½ from the other. Dolly In 1996, Dolly the sheep, a species much more complex than simple plants or bacteria, was cloned. She was the first fertile clone! This is the most famous cloning case to date. Genetic information from a FINN DORSET sheep. Enucleated ovum from a POLL DORSET sheep. Surrogate mother Blackface sheep. Offspring Clone of the FINN DORSET. Dolly showed signs of premature aging, possibly due to using specialized somatic cell nucleus. Genetic information from a FINN DORSET sheep. Enucleated ovum from a POLL DORSET sheep. Surrogate mother Blackface sheep. Offspring Clone of the FINN DORSET. ACT – Advanced Cell Technology ACT is a cell cloning company. It claims to have taken the first step in cloning a human embryo – an unborn baby in the first 8 weeks of development. The ACT clone didn’t grow beyond the tip of a ballpoint pen, only 6 cells What does the future hold? Other Clones Dolly the Sheep (1996) Tetra the Rhesus monkey (2000) Xena the Pig (2000) Alpha and Beta Male Cattle (2001) CC the Cat (2001) Idaho Gem & Utah Pioneer the Mules (03) Dewey the Deer (2003) Prometea the Horse (2003) Types of Cloning Recombinant DNA Cloning: Cloning a gene of particular interest. 2. Reproductive Cloning: Cloning that develops into a birth. (Stem cell) 3. Therapeutic cloning: Cloning with the goal of studying human development to treat disease. Is cloning a human being, part or whole, ethical or unethical? 1.