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Translation Translation • Converts/transfers information from mRNA into amino acids • Amino acids are the monomers of proteins • String amino acids together and a protein is made • 3 RNAs needed – mRNA (messenger—from nucleus to ribosome) – rRNA (ribosomal—used in the ribosome) – tRNA (transfer—transfers the codons into amino acids using anticodons) Translation 3 Main Steps 1. Initiation • mRNA attaches to the ribosome (with the use of rRNA) • rRNA reads the mRNA in groups of 3 nucleotides called codons • Translation starts with a special codon – AUG—start codon—initiator Translation 3 Main Steps 2. Elongation • tRNA carries specific amino acid to the ribosome • The specific amino acid is determined by the anticodon of tRNA • The anticodon pairs with complementary codon on mRNA (Example: codon AUG; anticodon UAC) • Peptide bonds form between amino acids, linking them into proteins • tRNAs get recycled back to go pick up more amino acids Translation amino acid tRNA **Draw this! anticodon codon protein (linked amino acids) ribosome Translation 3 Main Steps 3. Termination • Protein is released from ribosome when “stop codon” is reached – 3 stop codons: • UAA • UAG • UGA 1. mRNA codon chart Let’s Try!! 1. If mRNA codon is CCG, what is the amino acid? 2. If tRNA anticodon is AAC, what is the mRNA codon? What is the amino acid? 3. If the DNA template strand is ATA, what is the mRNA codon? What is the amino acid? 2. 3. Translation Answers 1. Proline 2. UUG ; leucine 3. UAU ; tyrosine Now…. 1. Use codon chart to complete practice worksheet 2. Draw/analyze/explain Figures: 17.12 17.15 17.16 17.23