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Cellular Respiration (not the breathing kind) Life is work… Performing work requires energy. At the cellular level, what form does that energy take? What process helps the cell make ATP? Cellular respiration. What is the summary equation for cellular respiration? C6H12O6 + O2 CO2 + H2O + 36- 38 ATP Is this all there is to it? Three processes that cause the release of the products in cellular respiration. What are the three process? Glycolysis The citric acid cycle (Krebs cycle) Oxidative Phosphorylation What organelle is required for the citric acid cycle and oxidative phosphorylation? The mitochondrion is where most of it goes down. Redox reactions Reduction. What is it? Remember OIL RIG. Something is reduced if it gains an electron. Oxidation. Something is oxidized if it loses an electron. When electrons move closer to a more electronegative atom, what happens? a. b. c.1. d. e. Energy is released. Energy is consumed. The more electronegative atom is reduced. The more electronegative atom is oxidized. A and C are correct. In redox reactions, what’s going on? One substance is a reducing agent, which means what? That it is the electron donor. One substance is an oxidizing agent, which mean what? That it is an electron acceptor. What is cellular respiration? The oxidation of glucose and other molecules in food to make energy available so that cells can complete their tasks, such as… Are your cells blowing up glucose all at once? NO! Series of enzymatic reactions that continually oxidize glucose in baby steps. A coenzyme (comes from a vitamin – what’s this again?) called NAD+ helps nibble, that’s right I said nibble, away electrons in small steps. Dehydrogenases play a role. What is it? What do dehydrogenases do to the pH of the surrounding solution? Why? Again, what are the three stages in cellular respiration? Glycolysis The citric acid cycle Oxidative phosphorylation (electron transport and chemiosmosis) Know the inputs and outputs of each. Glycolysis So old it _______ dust. What does it mean? Where does it happen? Got to contribute to get those bennies. Any oxygen needed here? What comes in and what goes out? Glucose, ATP, ADP, and NAD+ are the inputs. Pyruvate, NADH and ATP are kicked out. What happens to pyruvate in the presence of oxygen? What happens when no oxygen present? After glycolysis…if oxygen present, then… Once we’ve gained access, where and the heck are we… So, What’s up with the Acetyl CoA? Do you need to know this? No, but you do need to know the inputs and outputs… What’s going in? What’s coming out? Where is the stuff that is coming out going? To that last stage…the nasty one. Oxidative phosphorylation…yes! Where’s it happening? What’s going in? What’s coming out? Pictures are better. Electronegativity plays a role… How the ATP gets made – chemiosmosis (flow H+, flow) Go you proton motive force, go! In summary… Today’s question Cellular Respiration oxidizes glucose. What does it oxidize glucose to? Think about the summary equation. 36-38 ATP? Why can’t we have an exact system? Not all the H+ pumped out by the electrons shuttled by NADH and FADH2 are used to make ATP (they are used for other kinds of work). The ratio of NADH to ATP is wacky (10 H+ out for every one NADH, but we know what we don’t know. NADH from the cytosol made during glycolysis have issues. Fermentation Happens without ______ which is described as __________. What are the two kinds? Which organisms do which kind? Which one produces carbon dioxide? What else? Why is cellular respiration versatile? What ‘s up with biosynthesis? What does it require? Cellular Respiration is regulated just like all the others.