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Transcript
Nervous System Quiz
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1. Identify this structure (region
indicated, black).
or
n
0%
lh
Ve
nt
ra
icu
lf
un
Ve
nt
ra
Ep
en
dy
m
0%
...
na
.. .
0%
ca
ho
r
.
Do
rs
al
cu
l..
fu
ni
Do
rs
al
:30
0%
n
0%
al
A. Dorsal funiculis
B. Dorsal horn
C. Ependymal
canal
D. Ventral
funiculus
E. Ventral horn
2. Identify this structure (arrow, black).
or
n
0%
lh
Ve
nt
ra
icu
lf
un
Ve
nt
ra
Ep
en
dy
m
0%
...
na
.. .
0%
ca
ho
r
.
Do
rs
al
cu
l..
fu
ni
Do
rs
al
:30
0%
n
0%
al
A. Dorsal funiculis
B. Dorsal horn
C. Ependymal
canal
D. Ventral
funiculus
E. Ventral horn
3. Classify these 3 neuron types from
left to right.
0%
0%
po
l
ar
,b
Ps
i..
eu
.
do
un
ip
ol
ar
.. .
...
ly,
M
ul
ti
ar
,p
po
l
Bi
0%
ry
,C
ur
ul
t i.
..
ar
,m
Bi
po
l
:30
0%
se
ud
.. .
0%
La
r
A. Bipolar, multipolar,
pseudounipolar
B. Bipolar,
pseudounipolar,
multipolar
C. Larry, Curly, Moe
D. Multipolar, bipolar,
pseudounipolar
E. Pseudounipolar,
multipolar, bipolar
Dynein
Kinesin
Lipofuscin
Nissl substance
Perikaryon
0%
on
ar
y
Pe
r ik
nc
..
ub
st
a
Lip
:30
0%
.
0%
Ni
ss
ls
es
in
0%
Ki
n
Dy
ne
in
0%
of
us
cin
A.
B.
C.
D.
E.
4. What protein is primarily
responsible for axonal retrograde
flow?
5. You’ve just baked a beautiful apple pie. The smell
and taste of it are examples of peripheral nervous
system inputs sent to the CNS by …
Afferent neurons
Autonomic ganglia
Efferent neurons
Glial cells
Motor neurons
on
s
0%
ot
or
ne
ur
lc
M
Gl
ia
Ef
fe
re
nt
0%
el
ls
0%
...
g..
.
0%
ga
n
om
ic
Au
to
n
:30
Af
fe
re
nt
ne
ur
o
...
0%
ne
ur
o
A.
B.
C.
D.
E.
6. The apple pie from the previous question was too hot and
burned your finger when you touched it. A response by the CNS
is sent to skeletal muscle to retract your finger using …
Afferent neurons
Autonomic ganglia
Glial cells
Motor neurons
Pyramidal neurons
al
ne
ur
..
on
s
Py
ra
m
id
M
0%
.
0%
ot
or
ne
ur
el
ls
0%
lc
g..
.
0%
ga
n
om
ic
Au
to
n
:30
Af
fe
re
nt
ne
ur
o
...
0%
Gl
ia
A.
B.
C.
D.
E.
7. Multiple sclerosis is an auto-immune disorder which leads to
demyleination of axons and disruption of signal transduction.
The Schwann cell myelinates axons in the peripheral nervous
system. What cell performs the same function in the CNS?
A.
B.
C.
D.
E.
Astrocyte
Ependymal cell
Fibrous astrocyte
Microgliocyte
Oligodendrocyte
As
tro
:30
0%
0%
0%
0%
cy
te
Ep
en
dy
m
al
ce
ll
Fib
ro
us
as
tro
c..
.
M
icr
og
lio
cy
Ol
te
ig
od
en
dr
oc
yt
. ..
0%
8. The glia limitans is the outermost layer of proper
nervous tissue of the brain and spinal cord, underneath
the pia mater. Which neuroglial cell type primarily
forms this structure?
Ependymal cell
Fibrous astrocyte
Microglial cell
Oligodendrocyte
Protoplasmic
astrocyte
:30
0%
0%
0%
0%
0%
Ep
en
dy
m
al
ce
ll
Fib
ro
us
as
tro
c..
M
.
icr
og
lia
lc
el
Ol
.. .
ig
od
en
dr
oc
yt
. ..
Pr
ot
op
la
sm
ic
a.
..
A.
B.
C.
D.
E.
9. Identify this structure (arrow,
white).
Axon
Dendrite
Erythrocyte
Nissl body
Nucleolus
us
0%
Nu
cle
ol
od
y
0%
Ni
ss
lb
oc
yt
e
ite
0%
th
r
:30
0%
De
nd
r
Ax
on
0%
Er
y
A.
B.
C.
D.
E.
10. Identify this synapse type (circled,
red).
Axoaxonic
Axodendritic
Axosomatic
Postsynaptic
Presynaptic
Pr
es
yn
ap
Po
st
sy
na
p
0%
tic
0%
tic
0%
ic
on
i
Ax
oa
x
:30
0%
c
Ax
od
en
dr
iti
c
0%
Ax
os
om
at
A.
B.
C.
D.
E.
11. In this schematic diagram the presynaptic terminal is shown
releasing a neurotransmitter (yellow and orange spheres
indicated with white arrows) into a space termed the _____.
tic
cle
ft
Sy
na
p
Sy
na
p
tic
t..
0%
ve
s ic
.. .
0%
.
0%
tic
id
-sy
.
M
te
nt
i..
po
io
n
Ac
t
:30
0%
na
ps
e
0%
Po
st
sy
na
p
A. Action potential
space
B. Mid-synapse
C. Postsynaptic
terminal
D. Synaptic cleft
E. Synaptic vesicle
12. Glial fibrillary acidic protein, an intermediate filament
protein, is now known to be expressed in several cell types,
however, it is still identified as key marker for this CNS cell type.
A.
B.
C.
D.
E.
Astrocyte
Ependymal cell
Microgliocyte
Oligodendrocyte
Schwann cell
As
tro
:30
0%
0%
0%
0%
cy
te
Ep
en
dy
m
al
ce
ll
M
icr
og
lio
cy
Ol
te
ig
od
en
dr
oc
yt
. ..
Sc
hw
an
n
ce
ll
0%
13. Identify these cells (arrows, black).
Astrocytes
Fibrous astrocytes
Microgliocytes
Oligodendrocytes
Purkinje neurons
nj
en
cy
t. .
.
Pu
rk
i
Ol
ig
0%
eu
ro
...
0%
od
en
dr
o
cy
te
s
0%
og
lio
us
a
st
ro
c..
cy
te
s
Fib
ro
As
tro
:30
0%
.
0%
M
icr
A.
B.
C.
D.
E.
14. The choroid plexuses, which produce CSF,
are essentially specialized structures involving
which two epithelial cell types?
A. Endothelial cell + Fibroblast
B. Ependymal cell + endothelial
cell
C. Goblet cell + ependymal cell
D. Keratinocyte + endothelial
cell
E. Serous cell + Endocardium
.. .
Se
ro
us
c
el
l+
e+
t in
oc
yt
Ke
ra
el
l+
0%
...
0%
.. .
0%
et
c
Go
bl
al
lc
e.
..
Ep
en
dy
m
ot
he
lia
En
d
:30
0%
ce
ll.
..
0%
15. The neuroglial microgliocyte
derives from which blood-borne
precursor?
0%
Py
ra
m
id
al
nj
ec
ne
ur
..
el
l
.
0%
Pu
rk
i
ce
ll
0%
sm
a
on
oc
y
M
ph
a
ac
ro
M
:30
0%
te
0%
Pl
a
Macrophage
Monocyte
Plasma cell
Purkinje cell
Pyramidal
neuron
ge
A.
B.
C.
D.
E.
16. Which cellular junction is primarily
responsible for the formation of the blood-CSF
barrier within the choroid plexuses?
A.
B.
C.
D.
E.
Astrocyte
Desmosome
Fascia adherens
Gap junction
Zonula occludens
:30
0%
0%
0%
0%
De
sm
os
om
Fa
e
sc
ia
ad
he
re
n.
..
Ga
p
ju
nc
tio
Zo
n
nu
la
oc
clu
de
...
As
tro
cy
te
0%
17. Which cell type lines this space (arrow,
black)?
Astrocyte
Ependymal cell
Fibroblast
Purkinje neuron
Pyramidal cell
Central
Canal of
spinal cord
al
Py
ra
m
id
nj
en
bl
a
0%
ce
ll
0%
eu
ro
...
st
0%
Pu
rk
i
As
tro
:30
0%
cy
te
Ep
en
dy
m
al
ce
ll
0%
Fib
ro
A.
B.
C.
D.
E.
18. Classify this connective tissue (arrows, black).
Endocardium
Endoneurium
Endothelium
Perineurium
Percicardium
m
0%
rd
iu
ica
Pe
rc
Pe
r in
eu
r
ot
he
liu
En
d
0%
iu
m
0%
m
m
0%
on
eu
r iu
En
d
:30
oc
a
rd
i
um
0%
En
d
A.
B.
C.
D.
E.
20. Identify this cell of the spinal cord (arrow, black).
Astrocyte
Macrophage
Motor neuron
Purkinje cell
Pyramidal neuron
.
ne
ur
..
el
l
Py
ra
m
id
al
nj
ec
Pu
rk
i
ot
or
ne
ur
M
ph
a
ac
ro
M
As
tro
:30
on
ge
20% 20% 20% 20% 20%
cy
te
A.
B.
C.
D.
E.
21. Identify this cell (arrow, black).
Astrocyte
Dorsal root ganglion neuron
Oligodendrocyte
Primordial follicle
Schwann cell
0%
0%
ce
ll
n
an
Sc
hw
or
d
ial
fo
l
cy
t. .
.
...
0%
Pr
im
ro
ot
ga
. ..
0%
Ol
ig
:30
Do
rs
al
As
tro
cy
te
0%
od
en
dr
o
A.
B.
C.
D.
E.
22. The autonomic nervous system has 3 target
effectors – glands, cardiac muscle and ….
Astrocytes
Ependymal cells
Fibroblasts
Smooth muscle
Striated muscle
0%
0%
St
ri
at
ed
m
us
c le
m
us
c le
st
s
0%
bl
a
al
ce
lls
0%
Sm
oo
th
:30
Ep
en
dy
m
As
tro
cy
te
s
0%
Fib
ro
A.
B.
C.
D.
E.
23. Identify this layer (arrow, black).
Granular layer
Grey matter
Molecular layer
Purkinje layer
White matter
te
W
hi
ay
nj
el
Pu
rk
i
0%
m
at
te
r
0%
er
e.
..
0%
lar
ol
ec
u
Gr
ey
m
at
te
r
0%
M
:30
Gr
an
u
lar
lay
er
0%
lay
A.
B.
C.
D.
E.
200x
24. What is true of an efferent sympathetic impulse
from the ANS?
0%
Re
tro
gr
a
de
ax
o.
..
el
ls.
..
0%
nj
ec
Pu
rk
i
ub
st
a
nc
..
i..
.
n
0%
.
0%
eu
ro
Fir
st
n
:30
An
ax
on
is
no
t. .
.
0%
Ni
ss
ls
A. An axon is not needed
B. First neuron is always in
the CNS
C. Nissl substance is
destroyed
D. Purkinje cells are always
involved
E. Retrograde axonal flow
stops
25. Your patient received blunt head trauma that resulted in memory loss and
intracranial swelling. You suspect that cells of the brain were excessively
damaged. Which of the following cells phagocytize the cellular debris created
by neural damage?
Ependymal cells
Fibrous astrocytes
Microglial cells
Oligodendrocytes
Protoplasmic astrocytes
a.
..
pl
a
sm
ic
cy
t. .
.
Pr
ot
o
od
en
dr
o
el
..
lc
Ol
ig
og
lia
M
icr
st
ro
c..
us
a
Fib
ro
Ep
en
dy
m
al
:30
.
.
20% 20% 20% 20% 20%
ce
ll.
..
A.
B.
C.
D.
E.
26. Which of the following form the choroid plexus?
A. Arachnoid barrier cells
B. Ependymal cells and
endothelium
C. Meningeal dura
D. Pia mater and
arachnoid
E. Pia mater and the
overlying epithelium
Ar
a
:30
ch
no
id
ba
rr.
Ep
..
en
dy
m
al
ce
ll.
..
M
en
in
ge
al
du
ra
Pi
a
m
at
er
an
d
.. .
Pi
a
m
at
er
an
d
.. .
20% 20% 20% 20% 20%
27. Which of the following serve to allow CSF to exit
the subarachnoid space?
Arachnoid barrier cells
Arachnoid villi
Choroid plexus
Fenestrated capillaries
Vessels within the
subarachnoid space
in
. ..
w
ith
...
ca
Ve
ss
el
s
te
d
id
Fe
ne
st
ra
ll.
..
Ch
or
o
ch
no
id
vi
rr.
Ar
a
ba
ch
no
id
Ar
a
:30
pl
ex
us
20% 20% 20% 20% 20%
..
A.
B.
C.
D.
E.
28. A pathologist is examining a stained section of an unknown tissue. He
notices cells with an extremely large, flask-shaped body and multiple
dendrites lying in parallel. Which of the following tissues is the pathologist
examining?
A. Cerebellar cortex
B. Cerebral cortex
C. Gray matter of the
spinal cord
D. White matter of
cerebrum
E. White matter of the
spinal cord
...
m
at
te
ro
...
W
hi
te
m
at
te
ro
te
W
hi
m
at
t
er
o
f..
.
te
.. .
Gr
ay
lc
or
Ce
re
br
a
:30
Ce
re
be
lla
rc
or
...
20% 20% 20% 20% 20%
29. During early brain development, myelination of axons is a
critical event. Which of the following cells is responsible for this
important function?
Fibrous astrocytes
Microglial cells
Oligodendrocytes
Protoplasmic astrocytes
Schwann cells
ce
lls
n
an
Sc
hw
pl
a
sm
ic
cy
t. .
.
Pr
ot
o
.
od
en
dr
o
el
..
lc
Ol
ig
og
lia
M
icr
st
ro
c..
us
a
Fib
ro
:30
a.
..
20% 20% 20% 20% 20%
.
A.
B.
C.
D.
E.
32. Which of the following events occurs immediately
after an action potential reaches an axon terminal at
its synapse?
xa
tt
ns
he
m
Ne
...
i
t
ur
te
rb
ot
ra
in
ns
di
n.
m
Ve
..
it t
er
sic
le
re
le
fu
as
s io
e.
n
..
wi
th
th
e
p.
..
flu
io
n
c iu
m
Ca
l
Bi
:30
nd
i
ng
o
ft
he
ne
ur
ot
E.
ot
ra
D.
ra
.. .
C.
20% 20% 20% 20% 20%
in
B.
Binding of the neurotransmitter
to the presynaptic terminal
Calcium ion influx at the
presynaptic terminal
Neurotransmitter binding to the
receptor on the postsynaptic
terminal
Neurotransmitter release into the
synaptic cleft
Vesicle fusion with the
presynaptic terminal membrane
Ne
ur
A.
33. A 60-year old woman has suffered from a neurologic disorder for several
years. Analysis of the CSF revealed the presence of antibodies to myelin
proteins. From which of the following disorders does she suffer?
A. Amyotrophic lateral
sclerosis
B. Guillain-Barre
syndrome
C. Multiple sclerosis
D. Oligodendroglioma
E. Parkinson’s disease
.
di
..
so
n’
s
kin
gli
.. .
Pa
r
od
en
dr
o
pl
e
ul
ti
Ol
ig
e.
..
M
Gu
ill
ai
nBa
rr
a.
..
ic
l
tro
ph
yo
Am
:30
sc
le
r..
.
20% 20% 20% 20% 20%
34. A brain tumor is removed and analyzed by immunocytochemistry. It was
shown that the tumor expressed high levels of glial fibrillary acidic protein
(GFAP). Which of the following tumors was being analyzed?
Astrocytoma
Ependymoma
Meningioma
Neuroblastoma
Oligodendroglioma
As
tro
:30
20% 20% 20%
Ep
en
dy
m
om
a
M
en
in
gio
m
a
Ne
ur
ob
la
sto
m
Ol
a
ig
od
en
dr
og
li.
..
20% 20%
cy
to
m
a
A.
B.
C.
D.
E.
35. Tissue from the CNS of an 80-year old man is examined by electron
microscopy. Cells in this tissue sample have several residual bodies and
lipofuscin within their cytoplasm. Which of the following cells are being
described?
A. Astrocytes
B. Endothelial cells of
capillaries
C. Fibroblasts of dura
mater
D. Neurons
E. Oilgodendrocytes
cy
t. .
.
od
en
dr
o
on
s
Oi
lg
Ne
ur
f..
.
bl
a
st
so
lc
e.
..
ot
he
lia
Fib
ro
:30
En
d
As
tro
cy
te
s
20% 20% 20% 20% 20%
36. Which of the following cellular structures is found
within the cytoplasm of perikarya but is not within
axoplasm?
A. Membrane-bound
vesicles
B. Microtubules
C. Mitochondria
D. Neurofilaments
E. Rough endoplasmic
reticulum
M
as
.. .
en
do
pl
m
en
ts
of
ila
nd
ria
Ne
ur
M
ito
ch
o
ot
ub
ul
icr
M
Ro
ug
h
:30
em
br
a
ne
-b
ou
nd
.. .
es
20% 20% 20% 20% 20%
37. Which of the following structures prevent toxic
materials from attacking an axon of a peripheral
nerve?
Pe
r in
eu
r
ol
em
m
20%
iu
m
20%
a
20%
Ne
ur
m
on
eu
r iu
En
d
ch
w
of
S
Cl
ef
ts
:30
20%
ne
ur
iu
m
20%
Ep
i
Clefts of Schwann cells
Endoneurium
Epineurium
Neurolemma
Perineurium
...
A.
B.
C.
D.
E.
39. Which of the following is a primary component or
characteristic of a sensory ganglion?
A. Multipolar neurons
B. Neurons with eccentric
nuclei
C. Pseudounipolar
neurons
D. Scattered neuron cell
bodies
E. Synaptic contacts
ith
Ps
e.
..
eu
do
un
ip
ol
ar
Sc
.. .
at
te
re
d
ne
ur
Sy
...
na
pt
ic
co
nt
a.
..
w
on
s
Ne
ur
M
:30
ul
ti
po
l
ar
ne
u.
..
20% 20% 20% 20% 20%
41. Which of the following is the most critical event in
regeneration of a peripheral nerve?
A. Chromatolysis of the
damaged perikaryon
B. Distal axon degeneration
C. Hypertrophy of Schwann
cells
D. Phagocytic activity of
macrophages
E. Proliferation of Schwann
cells
. ..
t io
n
Pr
ol
ife
ra
ac
t..
.
ic
go
cy
t
yo
f. .
.
Ph
a
op
h
Hy
pe
rtr
xo
n
al
a
Di
st
:30
Ch
ro
m
at
ol
ys
is
...
de
...
20% 20% 20% 20% 20%
43. Which of the following components of the
meninges are most similar to the endoneurium that
covers a peripheral nerve?
Arachnoid border cells
Dural border cells
Meningeal dura
Pia mater
Subarachnoid space
s..
.
oi
d
a
ac
hn
Pi
a
m
Su
ba
r
M
en
in
ge
al
du
r
...
or
de
rc
Du
ra
lb
bo
ch
no
id
Ar
a
:30
at
er
20% 20% 20% 20% 20%
rd
...
A.
B.
C.
D.
E.
44. Which of the following best characterizes the
difference in myelinated axons of the PNS compared
with the CNS?
A. All axons have nodes of
Ranvier
B. All axons surrounded by
Schwann cells
C. No intraperiod line
D. No myelin basic protein
E. Schwann cells
myelinate at multiple
axonal cites
no
de
so
f. .
ur
.
ro
un
de
No
d
b.
in
..
tra
No
pe
rio
m
ye
d
lin
lin
Sc
e
ba
hw
s
ic
an
pr
n
ot
ce
ei
lls
n
m
ye
lin
at
e
..
ax
on
ss
av
e
Al
l
ax
on
sh
Al
l
:30
20% 20% 20% 20% 20%
45. Which of the following structures primarily
functions to monitor the degree of stretch of
muscles?
Golgi tendon organ
Merkel’s disk
Myoneural junction
Neuromuscular spindle
Pacinian corpuscle
rp
u.
..
..
Pa
c
in
ia
n
co
r.
.
om
us
cu
la
ju
nc
..
al
di
yo
ne
ur
M
er
ke
l’s
M
it
en
do
n
Go
lg
:30
Ne
ur
sk
20% 20% 20% 20% 20%
o.
..
A.
B.
C.
D.
E.
46. Which of the following cells of the PNS functions
equivalent to the oligodendrocyte within the CNS?
ce
lls
n
an
te
el
li
Sc
hw
ge
s
ac
ro
M
20% 20%
ce
ll.
..
20%
ph
a
bl
a
Fib
ro
ot
he
lia
En
d
:30
st
s
20% 20%
Sa
t
Endothelial cells
Fibroblasts
Macrophages
Satellite cells
Schwann cells
lc
e.
..
A.
B.
C.
D.
E.