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Wednesday May 29th
11.00-12.45
12.00-12.45
Registration
Lunch
12.45-13.00
13.00-15.00
P Andersen (Copenhagen) Introduction and Welcome
Innate immunity and Adjuvants
Chairman: A Harandi
R Lang (Erlangen) Recognition and reprogramming: innate immune response to
mycobacterial cord factor
V Hornung (Bonn) Intracellular DNA recognition by the innate immune system
S Paludan (Aarhus) Recognition of herpesviruses by the innate immune system
L Reinert (Aarhus) (Short talk) TLR3-deficiency renders astrocytes permissive to
herpes simplex virus infection and facilitates establishment of infection in the
CNS
15.00-15.30
Coffee / Tea
15.30-18.00
Immunity; Induction and quality
Chairman: F Zavala
SM Kaech (New Haven) Regulation of T cell responses during viral infection
JA Berzofsky (Maryland) Strategies and mechanisms for induction of mucosal T-cell
immunity
DE Speiser (Lausanne) Optimizing human T cell responses against cancer
M Boer (Leiden) (Short talk) CD39 is involved in mediating suppression by Mycobacterium bovis BCG-activated human CD8+CD39+ regulatory T-cells
DB Weiner (Philadelphia) (Short talk) Synthetic DNA Vaccine Technology, Application
to Persistent Infections
RP Sekaly, Québec) Systems biology of Vaccines : correlates and predictors of vaccine responses
M Boer (Leiden) (Short talk) CD39 is involved in mediating suppression by Mycobacterium bovis BCG-activated human CD8+CD39+ regulatory T-cells
18.30-20.00
Dinner
20.00-21.30
Poster session
Thursday May 30th
07.00
Breakfast
08.30-10.30
Adjuvants and vaccine delivery
Chairman: EM Agger
E De Gregorio (Siena) Novel TLR-dependent vaccine adjuvants
A Harandi (Gothenburg) Mucosal Vaccine Adjuvants: Hope or Hype
EM Agger (Copenhagen) Optimizing T cell responses for TB vaccines
F Verreck (Rijswijk) (Short talk) Comparative evaluation of the Cation Adjuvant Formulations CAF01 versus CAF09 in non-human primates
10.30-11.00
Coffee/tea
11.00-13.00
Vaccines and immune responses –Tuberculosis
Chairman: P Andersen
D Lewinsohn (Oregon) Recognition of the Mtb Infected Cell: CD8 T Cells Balance Innate and Adaptive Immunity
DL Woodland (Silverthorne) Maintenance of Peripheral T Cell Responses during Mycobacterium tuberculosis Infection
WJ Britton (Sydney) Protein vaccines against tuberculosis: new antigens and new
delivery strategies
A Cooper (New York) TB vaccination: do we know what we are trying to achieve at
a cellular level
13.15-14.15
Lunch
14.30-17.00
Therapeutic intervention in chronic diseases
Chairman: P thor Straten
IM Svane (Copenhagen) Treatment of melanoma patients by administration of in
vitro expanded tumor infiltrating lymphocytes (TIL); clinical and biological
evaluation
A Salanti (Copenhagen) Targeting cancer user evolutionary refined pathogen derived proteins
C Melief (Leiden) Synthetic vaccines for established lesions caused by chronic virus infection
E John Wherry (Philadelphia) Regulating and maintaining CD8 T cell responses during chronic infection
PJ Cardona (Barcelona) (Short talk) Deciphering the progression towards active TB
18.30-20.00
Dinner
20.00-21.30
Poster sessions
Friday May 31st
7.00
Breakfast
08.30-10.30
Vaccines and immune responses - Malaria
Chairman: L Hviid
F Zavala (Maryland) Protective CD8+ T cell responses against malaria liver stages
EM Riley (London) Natural Killer cells as mediators of vaccine-induced immunity
M Mota (Lisbon) Host cell sensors for Plasmodium activate innate immunity
against liver stage infection
L Stevenson (Copenhagen) (Short talk) The role of non-specific IgM binding to a
PfEMP1 protein mediating rosetting
10.30-11.00
Coffee / tea
11.00-13.00
Immunological memory and effector cells
Chairman: AR Thomsen
R Malley (Boston) B and T cell immunity to Streptococcus pneumoniae: Implications for Vaccine Development
JP Christensen/AR Thomsen (Copenhagen) Adenovirus induced CD8 T cell memory
and protection against disease?
T Hussell (London) Epithelial regulation of innate immunity in the lung
T. Lindenstrøm (Copenhagen) (Short talk) Control of chronic M. tuberculosis infection by CD4 KLRG1- IL-2 secreting central memory cells induced by an adjuvanted subunit vaccine
13.00-14.00
Lunch
14.00-15.50
Vaccines and immune responses - HIV
Chairman: A Fomsgaard
R Shattock (London) Optimising humoral responses for HIV prevention
B Autran (Paris) Therapeutic vaccination in strategies for functional cure of HIV
G Pantaleo (Lausanne) Viral vectors in the development of HIV vaccines
DB Weiner (Philadelphia) (Short talk) Synthetic DNA Vaccine Technology, Application to Persistent Infections
16.00
Meeting closes
16.15
18.15
19.15
Bus to Statens Serum Institut, Copenhagen – Reception building 33
Bus to The Workers' Museum, Copenhagen
Conference dinner - The Workers' Museum