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220.127.116.11.1. 1.2.4. Prescriber should be contacted prior to initiating graded challenge 18.104.22.168.2. Anaphylaxis treatment medications should be available The pharmacist should contact the prescriber if: 22.214.171.124. The type of rash cannot be ascertained, in which case it should be assumed to be urticarial (IgG mediated).11 126.96.36.199. The patientâs history is positive for an IgE-mediated (type 1) reaction. 188.8.131.52. The reaction is a severe, non-IgE-mediated reaction.