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Electroconvulsive therapy (ECT) for depressive illness, schizophrenia, catatonia and mania
Electroconvulsive therapy (ECT) for depressive illness, schizophrenia, catatonia and mania

... current through a person’s brain while they are under a general anaesthetic and have been given a muscle relaxant. This normally produces a convulsion. A course of ECT usually consists of six to twelve treatments given twice a week. ECT is indicated for severely depressed patients, but is also has a ...
Mephedrone
Mephedrone

... 10. Listing on the WHO Model List of Essential Medicines .....................................................................................22 11. Marketing authorizations (as a medicine) ............................................................................................................22 ...
MICROMEDEX® Healthcare Series _ Document
MICROMEDEX® Healthcare Series _ Document

... milligrams (mg) orally once daily, administered in the morning. Studies suggest that doses of 20 mg daily may be sufficient to obtain a satisfactory antidepressant response. If no clinical improvement is observed after several weeks, the dosage can be increased at intervals of several weeks, not to ...
ziprasidone - PsychSearch
ziprasidone - PsychSearch

... 1.3.1.A.1.b Schizophrenia 1) For SCHIZOPHRENIA the initial daily dose is 20 milligrams (mg) twice daily with food. In some patients daily dosage may be adjusted up to 80 mg twice daily. Adjustments, if indicated, should occur at intervals of not less than 2 days. Efficacy in short-term clinical tria ...
clozapine - Law Project for Psychiatric Rights
clozapine - Law Project for Psychiatric Rights

... and a divided dosage schedule are necessary to minimize the risks of hypotension, seizures, and sedation. 2) If therapy is interrupted for two days or more, clozapine should be reinitiated at a dose of 12.5 milligrams once or twice daily. If well-tolerated, titration to the therapeutic dose may proc ...
The role of drugs in the pathogenesis of gingival overgrowth
The role of drugs in the pathogenesis of gingival overgrowth

... The pathogenic mechanisms responsible for phenytoin-associated gingival overgrowth remain undisclosed. In vitro studies have investigated the effect of phenytoin on human gingival fibroblasts in tissue culture (155, 178, 179). Shafer (155) reported that the optimal rate of cell growth (2x1occurred a ...
ANNEXURE-3 14
ANNEXURE-3 14

... Appropriate cultures should usually be performed before initiating antimicrobial treatment in order to isolate and identify the organisms causing infection and to determine their susceptibility to piperacillin and tazobactam. Antimicrobial therapy should be adjusted, if appropriate, once the results ...
Guidelines for ATC classification and DDD assignment
Guidelines for ATC classification and DDD assignment

... access to needed drugs and rational use of drugs particularly in developing countries. Access to standardised and validated information on drug use is essential to allow audit of patterns of drug utilization, identification of problems, educational or other interventions and monitoring of the outcom ...
The safety of hydroquinone
The safety of hydroquinone

... proposing a ban on over-the-counter (OTC) hydroquinone. Specifically, the FDA proposes to ‘‘establish that over-the-counter (OTC) skin bleaching drug products are not generally recognized as safe and effective (GRASE).’’ The FDA also ‘‘intends to consider all skin bleaching products, whether current ...
TRIAMTERENE and HYDROCHLOROTHIAZIDE TABLETS, USP
TRIAMTERENE and HYDROCHLOROTHIAZIDE TABLETS, USP

... and rats during respective periods of major organogenesis at doses up to 3000 and 1000 mg/kg/day, respectively. At these doses, which are multiples of the MRHD equal to 3000 for mice and 1000 for rats, based on body-weight, and equal to 282 for mice and 206 for rats, based on body-surface area, ther ...
Therapeutic monitoring of vancomycin in adult patients
Therapeutic monitoring of vancomycin in adult patients

... adjusting of serum vancomycin drug concentrations has been the subject of intense debate for many years.5-9 The controversy has resulted from conflicting evidence regarding the use of serum vancomycin concentrations to predict and prevent druginduced toxicity and as a measure of effectiveness in tre ...
Therapeutic Monitoring of Vancomycin in Adult Patients
Therapeutic Monitoring of Vancomycin in Adult Patients

... Early use of vancomycin was associated with a number of adverse effects, including infusion-related toxicities, nephrotoxicity, and possible ototoxicity. Upon further investigation, it appears that the impurities in early formulations of vancomycin caused many of these adverse events.1-4 Its overall ...
Pharmacokinetic interactions of carbamazepine with some
Pharmacokinetic interactions of carbamazepine with some

... topiramate (TPM), vigabatrin (VGB) or valproic acid (VPA) in children and adolescents treated for epilepsy. Material and methods: The participants of the presented investigations were fifty-five patients with epilepsy who were under control of The Department of Developmental Neurology, University of ...
SERETIDE ACCUHALER/DISKUS™
SERETIDE ACCUHALER/DISKUS™

... Salmeterol acts locally in the lung therefore plasma levels are not an indication of therapeutic effects. In addition there are only limited data available on the pharmacokinetics of salmeterol because of the technical difficulty of assaying the drug in plasma due to the low plasma concentrations at ...
Australian Public Assessment Report for Dutasteride/Tamsulosin
Australian Public Assessment Report for Dutasteride/Tamsulosin

... Non-compliance with medication is a common problem, and elderly patients with multiple comorbidities potentially face many barriers to compliance. These may include confusion, reduced dexterity, and increased number of concurrent medications. 13 Therefore, any potential reduction in pill burden may ...
levocarb CR
levocarb CR

... altered by boiling the urine specimen. False-negative tests may result with the use of glucoseoxidase methods of testing for glucosuria. Cases of falsely diagnosed pheochromocytoma in patients with levodopa/carbidopa therapy have been reported very rarely. Caution should be exercised when interpreti ...
(2008). Nonresponse and dropout rates in outcome
(2008). Nonresponse and dropout rates in outcome

... Only a minority of patients presenting with PTSD can undergo trauma-focused interventions which produce iatrogenic effects and trigger therapy dropout. Clinical trials do not reflect clinical practice and patients’ needs and fragilities. In this book, my intention is to remind all of us, with ample ...
PACIFIC BUSPIRONE Presentation NEW ZEALAND DATA SHEET
PACIFIC BUSPIRONE Presentation NEW ZEALAND DATA SHEET

... psychomotor impairment. However, its CNS effects in any individual patient may not be predictable. Therefore, patients should be cautioned about driving a vehicle or using complex machinery until they are certain that buspirone treatment does not affect them adversely. While formal studies of the in ...
Salvia Divinorum
Salvia Divinorum

... medical studies undertaken to examine the drug's physiological effects have focused only on short-term effects. However, information provided by abusers indicates that the negative longterm effects of Salvia Divinorum may be similar to those produced by other hallucinogens such as LSD (lysergic acid ...
Canadian Headache Society Guideline for Migraine Prophylaxis
Canadian Headache Society Guideline for Migraine Prophylaxis

... randomized, double blind, controlled trials of drug treatments for migraine prophylaxis and relevant Cochrane reviews were identified. Studies were graded according to criteria developed by the US Preventive Services Task Force. Recommendations were graded according to the principles of the Grading ...
Drug utilisation sub-committee (DUSC)
Drug utilisation sub-committee (DUSC)

... A clinically important product-related adverse event is defined as follows: (i) Severe myalgia (muscle symptoms without creatine kinase elevation) which is proven to be temporally associated with statin treatment; or (ii) Myositis (clinically important creatine kinase elevation, with or without musc ...
AusPAR: Dapagliflozin - Therapeutic Goods Administration
AusPAR: Dapagliflozin - Therapeutic Goods Administration

... An AusPAR is a static document, in that it will provide information that relates to a submission at a particular point in time. ...
Methotrexate - Pfizer Canada
Methotrexate - Pfizer Canada

... Methotrexate has the potential for acute and chronic hepatotoxicity. Acutely, liver enzyme elevations are frequently seen after Methotrexate administration and are usually not a reason for modification of Methotrexate therapy. Liver enzyme elevations are usually transient and asymptomatic, and also ...
Ewrramt~amm=nts I
Ewrramt~amm=nts I

... But another type of aspirin-antacid combination tablet may reduce stomach damage. Some aspinn products are enteric-coated. This prevents the aspirin tablet from dissolving until it reaches the intestines. The intestinal walls are less likely to be harmed by aspirin, presumably because they are more ...
34 ECDD 2006/4.3         ...
34 ECDD 2006/4.3 ...

... Ketamine differs from most anaesthetic agents in that it appears to stimulate the cardiovascular system, producing changes in heart rate, cardiac output, and blood pressure (Haas and Harper, 1992). Possibly re-uptake inhibition of circulating catecholamines may contribute to this phenomenon. On the ...
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Psychedelic therapy

Psychedelic therapy refers to therapeutic practices involving the use of psychedelic drugs, particularly serotonergic psychedelics such as LSD, psilocybin, DMT, mescaline, and 2C-B, primarily to assist psychotherapy. As an alternative to synonyms such as ""hallucinogen"", ""entheogen"", ""psychotomimetic"" and other functionally constructed names, the use of the term psychedelic (""mind-manifesting"") emphasizes that those who use these drugs as part of a therapeutic practice believe these drugs can facilitate beneficial exploration of the psyche. In contrast to conventional psychiatric medication which is taken by the patient regularly or as-needed, in psychedelic therapy, patients remain in an extended psychotherapy session during the acute activity of the drug and spend the night at the facility. In the sessions with the drug, therapists are nondirective and support the patient in exploring their inner experience. Patients participate in psychotherapy before the drug psychotherapy sessions to prepare them and after the drug psychotherapy to help them integrate their experiences with the drug.According to one Canadian study conducted in the early years of the 1960s, the greatest interest to the psychiatrist was the fact that LSD allowed for the ""illusional perception ('reperception') of the patient's original family figures (e.g. father, mother, parent surrogates and helpers, older siblings, grandparents and the like)"", typically experienced as distortions of the psychiatrist's face, body or activity. In technical terms, this was called ""perceptualizing the transference"".
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