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Unit 6 Review: Answer Key DNA Structure 1. 3 components that make up a nucleotide: Phosphate group, deoxyribose (sugar), nitrogen base 2. Chargaff’s Rule: The amount of adenine always equals that of thymine and the amount of guanine always equals that of cytosine (%A = %T) (%G = %C) DNA Replication 3. G G C A T T A C 4. DNA Transcription 1. DNA is copied into mRNA 2. RNA polymerase makes copy 3. Uracil in place of thymine 4. 1 strand is copied 1. 2. 3. 4. DNA Replication DNA is copied to DNA DNA polymerase makes copy thymine 2 strand are copied DNA Transcription 5. DNA 1. Thymine 2. 2 strands 3. deoxyribose sugar RNA 1. Uracil 2. 1 strand 3. ribose sugar 6. Transcription produces: mRNA 7. Transcription takes place in the nucleus. 8. One codon makes up an amino acid. 4 codons are needed to make up 4 amino acids. 9. One DNA strand is coped by mRNA during transcription DNA Translation 10. mRNA gets read by tRNA and produces an amino acid 11. Chains of amino acids form genes which give instructions to produce proteins. 12. The AUG codon codes for start/methionine Mutations 13. Substitutions: point mutation insertions and deletions: frameshift mutations 14. Normal DNA: DNA: AAT TCG CCG GTA TTA GAC GTT TTA AAU AGC UCG GGC CCG CAT GUA AAT UUA CTG GAC CAA GUU serine proline valine leucine Aspartic acid valine mRNA: Amino Acid: Asparagine Insertion: dramatic effect DNA: AAT ATC mRNA: Amino Acid: TTA AAU asparagine isoleucine Deletion: dramatic effect DNA: AAT mRNA: Amino Acid: TAG AUC GCC GGT ATT AGA CGT T CGG GCC CCA GGU TAA AUU TCT AGA GCA CGU A U alanine glycine isoleucine arginine arginine CGC CGG TAT TAG ACG TT TTA AAU GCG UGC GCC CGG ATA UAU ATC UAG TGC ACG AA UU asparagine cysteine argininine tyrosine stop threonone Substitution: no effect DNA: AAT TCA CCG GTA TTA GAC GTT TTA AAU AGT UCA GGC CCG CAT GUA AAT UUA CTG GAC CAA GUU asparagine serine proline valine leucine Aspartic acid mRNA: Amino Acid: valine