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Transcript
Internal Medicine
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Pericardial effusion and ascites occasionally occur
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Constipation
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Menorrhagia,
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Memory impairment
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Psychosis may develop with long-standing hypothyroidism and may be precipitated by
thyroid hormone replacement
Physical examination
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Thickened, puffy features is due to accumulation of mucinous mucoplysaccharide-rich
material in tissues .This is known and myxedema
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Yellowish dry skin
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Nonpitting edema
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Hypothermia
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Bradycardia
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A delay in return phase of Achilles and other deep tendon reflexes is a specific finding.
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Loss of the lateral portion of the eyebrows ( madarosis )
Effect of hypothyroidism on organ systems
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Cardiovascular system : Decrease in cardiac output ,Pericardial effusion
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Respiratory system : Hypoventilation ,Plural effusion
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Gastrointestinal tract : Constipation
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Nervous system: Decreased mental function , Psychiatric changes ( e.g. psychosis ,
depression )
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Blood: Normocytic normochromic anemia.
Cretinism: is sever hypothyroidism beginning in infancy infants may have
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Hypotonia, umbilical hernia,
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Delayed mental and physical development, and mental retardation may result if
hypothyroidism goes untreated in the first few years of life.
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Shot limbs and a large head , with a bread flat nose , widely set eyes , and a large
tongue characterize this form of dwarfism
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Other signs and symptoms typical of adult patients may also be seen
Diagnostic workup:
Thyroid function tests:
1. Serum TSH level:
466