Download Internal Medicine - The Carter Center

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project

Document related concepts

Infection wikipedia, lookup

Disease wikipedia, lookup

Management of multiple sclerosis wikipedia, lookup

Multiple sclerosis research wikipedia, lookup

List of medical mnemonics wikipedia, lookup

Dental emergency wikipedia, lookup

Sjögren syndrome wikipedia, lookup

Adherence (medicine) wikipedia, lookup

Syndemic wikipedia, lookup

Focal infection theory wikipedia, lookup

Transcript
Internal Medicine
2. Red blood cell indices
a. Mean Corpuscular volume ( MCV): Hct/RBC : normal value is 80 – 95 fl
b. Mean corpuscular Hemoglobin( MCH ) : Hgb/RBC : 27 – 32 pg
c. Mean corpuscular Hemoglobin (MCHC): Hgb/Hct 32 – 36%
3. Examination of the peripheral blood smear: examine a cellular morphology, shape,
size, color, abnormality of other cells.
Red cell morphology
•
Normochromic Normocytic RBCs are aeen in normal individuals and in anemia of
chronic diseases
•
Anisopoikilocytes: Variation in size and shape may be seen in iron deficiency anemia
•
Hypochromic microcytic anemia: is seen in iron defeciency anemia , anemia of
chronic diseases , thalassemia and sideroblastic anemia (SBA)
•
Macrocytic RBCs : Macro – ovalocytes with hyper segmented neutrophils Æ indicate
megaloblastic anemia and myelodysplasia
•
Schistocytes (fragmented RBC/Helmentcells):- microangiopathies , DIC, vasculitis,
prosthetic heart valve
Classification of anemia
A. Pathophyisiologic Classifications (based on underlying disease)
1)
Anemia associated with impaired RBC Production
a) Aplastic anemia
b) Iron deficiency
c) Myelodysplastic syndrome.
d) Megaloblastic anemia
e) Anemia of CRF
f) Anemia of chronic diseases
g) Drug related
2) Anemia associated with increased RBC loss or destruction
a) Bleeding
b) Hereditary hemolytic anemia
i)
Hemoglobinopathies, sickle cell disease, Thalassemia
ii) Primary disorder of RBCs
iii) RBC erythropathies (G6 PDH, PK deficiency)
c) Acquired hemolytic anemia
392