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Protein Diagram
The diagram below shows a portion of a protein bound to a nucleotide structure. There are multiple
interactions that bind the substrate to this active site. From the following choices correctly choose which
answer correctly characterizes the shown interactions.
A.
B.
C.
D.
E.
F.
1- shows a side chain interacting with the substrate through hydrogen bond
2- shows a backbone interaction to the substrate
3- shows a backbone interaction to the substrate
4- shows a polar side chain interacting with a polar region of the substrate
5 –shows a polar side chain interaction to the substrate
1 - shows a non-polar sidechain interacting with the substrate
Combination
A & B are true ets
Protein Diagram Question 2
Which of the following choices the same amino acid?
A.
B.
C.
D.
E.
F.
G.
1 and 7
1 and 8
1 and 5
6 and 7
7 and 8
5 and 6
2 and 1
Which of the following represent the correct order of shown amino acids from Amino (-NH3) terminus
to carboxyl terminus (-COOH)?
A.
B.
C.
D.
E.
F.
G.
-NH3…Serine….Tryptophan……Serine….Proline, Phenyalanine…-COOH
–NH3….S….T….E….R,S…-COOH
–NH3…Ala…Met….Phe….Gln, Ser…-COOH
–NH3….Glycine….Glutamine…. Valine…..Histidine, Isoleucine ….-COOH
–NH3…..Ser….Thr….Glu….Arg, Ser….-COOH
None of the above
Both B and E are correct
The sidechains lining the active site cleft of this protein are specific to bind this substrate. Which of the
following would be most disruptive for the function of the protein?
A.
B.
C.
D.
E.
F.
G.
Residue 7 to Asn
Residue 5 to Asn
Residue 5 to Thr
Residue 6 to Asp
Residue 6 to Lys *
Residue 1 to Trp *
Residue 8 to Val*
If you added a non-polar substance into this container with some significant stirring, predict where you
find