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Transcript
3. Substrate binding
3.2 Bonding forces
•
Induced fit - Binding site alters shape to maximise
intermolecular bonding
Phe
Phe
O
O
H
Ser
CO2
Asp
Intermolecular bonds not
optimum length for
maximum binding strength
Induced
Fit
Ser
H
CO2
Asp
Intermolecular bond
lengths optimised
©1