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Transcript
Mutating your DNA (1) Name: Codon 1 Your ORIGINAL deoxyribonucleic acid sequence (for the left strand): Write the ORIGINAL sequence for the complementary strand (right strand): Codon 2 Codon 3 Codon 4 G T T T A A bottom A T G G C T bottom __ __ __ __ __ __ __ __ __ __ __ __ top top Transcribe to a left strand mRNA, then translate and Write the amino acid sequence A(n) __________________________________ mutation occurs during replication Codon 1 your REPLICATED deoxyribonucleic acid sequence (for the left strand): Write the REPLICATED sequence for the complementary strand (right strand): Codon 2 Codon 3 Codon 4 G T T T A A bottom A T G G C A bottom __ __ __ __ __ __ __ __ __ __ __ __ top Transcribe to a left strand mRNA, then translate and Write the amino acid sequence Describe the effect of the mutation on the right strand DNA: Describe the effect of the mutation on the protein: Explain why the mutation had this effect: top Codon 1 Your ORIGINAL deoxyribonucleic acid sequence (for the left strand): Write the ORIGINAL sequence for the complementary strand (right strand): Codon 2 Codon 3 Codon 4 G T T T A A bottom A T G G C T bottom __ __ __ __ __ __ __ __ __ __ __ __ top top Transcribe to a left strand mRNA, then translate and Write the amino acid sequence A(n) __________________________________ mutation occurs during replication Codon 1 your REPLICATED deoxyribonucleic acid sequence (for the left strand): Write the REPLICATED sequence for the complementary strand (right strand): bottom A T G bottom __ __ __ Codon 2 Codon 3 Codon 4 C T G T T T A A __ __ __ __ __ __ __ __ Transcribe to a left strand mRNA, then translate and Write the amino acid sequence Describe the effect of the mutation on the right strand DNA: Describe the effect of the mutation on the protein: Explain why the mutation had this effect: top top Codon 1 Your ORIGINAL deoxyribonucleic acid sequence (for the left strand): Write the ORIGINAL sequence for the complementary strand (right strand): Codon 2 Codon 3 Codon 4 G T T T A A bottom A T G G C T bottom __ __ __ __ __ __ __ __ __ __ __ __ top top Transcribe to a left strand mRNA, then translate and Write the amino acid sequence A(n) __________________________________ mutation occurs during replication Codon 1 your REPLICATED deoxyribonucleic acid sequence (for the left strand): Write the REPLICATED sequence for the complementary strand (right strand): Codon 2 Codon 3 Codon 4 G T T T A A bottom A T G G G T bottom __ __ __ __ __ __ __ __ __ __ __ __ top Transcribe to a left strand mRNA, then translate and Write the amino acid sequence Describe the effect of the mutation on the right strand DNA: Describe the effect of the mutation on the protein: Explain why the mutation had this effect: top Codon 1 Your ORIGINAL deoxyribonucleic acid sequence (for the left strand): Write the ORIGINAL sequence for the complementary strand (right strand): Codon 2 Codon 3 Codon 4 G T T T A A bottom A T G G C T bottom __ __ __ __ __ __ __ __ __ __ __ __ top top Transcribe to a left strand mRNA, then translate and Write the amino acid sequence A(n) __________________________________ mutation occurs during replication Codon 1 your REPLICATED deoxyribonucleic acid sequence (for the left strand): Write the REPLICATED sequence for the complementary strand (right strand): Codon 2 Codon 3 Codon 4 T G T T T A bottom A T G G G C bottom __ __ __ __ __ __ __ __ __ __ __ __ Transcribe to a left strand mRNA, then translate and Write the amino acid sequence Describe the effect of the mutation on the right strand DNA: Describe the effect of the mutation on the protein: Explain why the mutation had this effect: A top __ top If one or more mutations caused the second codon to be either TAA, TAG or UGA, describe the protein resulting from this nonsense substitution: Compare and contrast silent and missense substitution mutations Describe the similarity in how many nucleotides they affect: Describe the difference in how many amino acids they affect: Describe why some substitutions are silent: Explain what missense means: Compare insertion and deletion mutations Describe the similarity in how they affect nucleotides after (right of) the mutation: Describe how the changes in nucleotides affect amino acids after (right of) the mutation: Contrast insertion and deletion mutations with silent and missense substitutions Describe the difference in how many amino acids these mutations affect: Contrast nonsense substitutions with other mutations Explain what a nonsense substitution is AND how it affects the protein differently from other mutations:
