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EMBO ER Conference Short Talks Oct 4th, Monday Translocation Salomé Calado Botelho Comparison of transmembrane domain recognition between Sec61 translocon and TIM23 complex Authors: Salomé Calado Botelho, Marie Österberg, Hyun Kim, Gunnar von Heijne ER Associated Degradation: Pedro Carvalho Retro-translocation of a Misfolded Luminal ER Protein by the Ubiquitin-ligase Hrd1p Authors: Pedro Carvalho, Ann Marie Stanley, Tom Rapoport Glycosylation Veit Goder Protein O-mannosyltransferases participate in ER protein quality control by diverting proteins from ER export to ER-associated protein degradation (ERAD) Authors: Veit Goder, Alejandro Melero Oct 5th, Tuesday Disulfide Bond and Other Modifications: Robert Gauss A complex of Pdi1p and Htm1p initiates clearance of unfolded glycoproteins from the endoplasmic reticulum Authors: Robert Gauss, Kazue Kanehara, Pedro Carvalho, Davis T.W. Ng, Markus Aebi Proteomics/High Throughput Approaches Michael Bassik Exploring the regulation of protein homeostasis using genetic interaction maps Authors: Michael Bassik, Martin Jonikas, Martin Kampmann, L. Stirling Churchman, Robert Jan Lebbink, Weronika Patena, Michael McManus, Maya Schuldiner, Jonathan Weissman October 6th, Wednesday Ion Homeostasis Éva Margittai1 Hydrogen peroxide formation in the endoplasmic reticulum – double edge sword in oxidative protein folding Authors: Éva Margittai, Roberto Sitia, Gábor Bánhegyi UPR (PLEASE NOTICE THERE ARE THREE TALKS HERE) Maho Niwa ER stress surveillance response Authors: Anna Babour, Alicia Bicknell, Joel Tourtellotte, Maho Niwa AND Yair Argon Genetic ablation of GRP94 or mutants with reduced activity profoundly affect animal growth, because of decreased capacity to support production of Insulin-like Growth Factors Authors: Yair Argon, Olga Ostrovsky, Davide Eletto, Michal Marzec, Gil Atzmon, Adda Grimberg AND John Christianson Defining the functional complexes of mammalian ERAD Authors: John C. Christianson, James A. Olzmann, Thomas A. Shaler, Mathew E. Sowa, Eric J. Bennett, Caleb M. Richter, Ryan E. Tyler, Ethan J. Greenblatt, J. Wade Harper, Ron R. Kopito Chaperones and Folding Kalle Gehring Structural insights into the function of the P-domains of lectin chaperones Authors: Kalle Gehring, Guennadi Kozlov October 7th, Thursday Trafficking Manuel Muñiz The yeast p24 complex regulates GPI-anchored protein ER exit through a quality control function Guillaume A. Castillon, Auxiliadora Aguilera-Romero, Sharon Epstein, Javier Manzano, Kentaro Kajiwara, Kouichi Funato, Reika Watanabe, Howard Riezman, Manuel Muñiz Architecture of ER Dan Zhang The cortical ER network limits the permissive zone for actomyosin ring assembly Authors: Dan Zhang, Aleksandar Vjestica and Snezhana Oliferenko ER in Development and Disease Markus Zettl Rhomboid family pseudoproteases exploit the ER quality control machinery to control intercellular signalling Authors: Markus Zettl, Colin Adrain, Kvido Strisovsky and Matthew Freeman