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1-The signs of poisoning with organophosphorous anticholinesterase insecticides do NOT include: a. Bronchoconstriction b. Mydriasis c. Intestinal spasm d. Increased bronchial secretions 2--The cholinomimetic drug that is useful for treating postoperative abdominal distention and gastric atony is:a) b) c) d) Acetylcholine Bethanechol Pilocarpine Methacholine 1-Edrophonium: T a. inhibits the action of cholinesterase in the neuromuscular junction T b. has little effect if given orally T c. is used in the diagnosis of myasthenia gravis T d. causes bradycardia 2. Atropine: F a. blocks nicotinic acethylcholine receptors T b. dries bronchial and salivary secretion T c. is used to avoid unwanted side effects of neostigmine T d. causes loss of accommodation Antiyhperlipidemic MCQ What is the mechanism of action of cholestyramine?-a-sequesteration of bile acid b-decreased hepatic secretion of VLDL c-increased lipoprotein lipase activity d-inhibition of HMG-CoA reductase Antiyhperlipidemic T/F -Gemfebrozil:a-function as a ligand for peroxisome proliferator-activated receptor-alpha T b- inhibits lipoprotein lipaseF T c-lowers plasma triglycerides d-causes myopathyT Angina pectoris MCQ -The therapeutic action of propranolol in angina pectoris is believed to be primarily the result of:a-reduced production of catecholamines b-dilatation of coronary vessels. c-decreased myocardial oxygen demand d-increased peripheral resistance Angina pectoris T/F -The management of unstable angina usually includes:a-aspirinT b-glyceryltrinitrateT Tc-alpha adrenoceptors antagonists Td-intravenous heparin Corticosteroids MCQ -Which of the following glucocorticoids is used to suppress ACTH production in order to determine that cortisol production is independent of the pituitary gland? a-triamcinolone b-prednisone c-hydrocortisone d-dexamethasone Corticosteroids T/F Chronic administration of corticosteroids results in:a-increased susceptibility to infectionT b-hyperkalaemiaF c-hypotensionF T d-cataracts Gout T/F Allopurinol:a-inhibits xanthine oxidaseT b-may provoke acute goutT Fc-inactivates azathioprine Fd-should not be prescribed with an NSAID Parkinsonism MCQ -Carbidopa is useful in treatment of Parkinson's disease because it:-a-is a precursor of levodopa b-is a dopamine receptor agonist c-prevents breakdown of dopamine d-prevents peripheral biotransformation of levodopa Sedative hypnotics MCQ -Which of the following is described as competitive benzodiazepine receptor antagonist? a-chlordiazepoxide b-flumazenil c-zaleplon d-zolpidem Malaria MCQ -Which of the following agents should be used to eradicate the extraerythrotic phase of P.vivax? a-pyrimethacine b-primaquine c-mefloquine d-artesonate Cytotoxic drugs MCQ 1-The phase of the cell cycle that is resistant to most chemotherapeutic agents and required increased dosage to obtain a response is the:a) M phase b) G2 phase c) S phase d) G0 phase e) G1 phase