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Name: Date: Class Period: Meiosis and Mendelian Genetics Vocabulary _________________________________: the passing on of traits genetically from one generation to another. _________________________________: the scientific study of heredity _________________________________: a specific characteristic that varies from one individual to another _________________________________: the chance that a particular event will happen _________________________________: a diagram that shows the gene combinations that might occur when two parents make offspring _________________________________: having two identical alleles for a particular trait (aa or AA) _________________________________: having two different alleles for a particular trait (Aa) _________________________________: the physical characteristics of an organism (such as brown hair, freckles, or a big nose) _________________________________: the genetic make-up of an organism (AA, Aa, or aa) _________________________________: a gene that can cover up the phenotype of a recessive allele _________________________________: a gene whose trait can only be seen if there are no dominant alleles present 1 Meiosis Review Recall that during meiosis, ________________________ _____________________________ pair up in the middle of the cell to form ________________________ and cross over, leading to new combinations of genes on each chromatid. The four ___________________ from the tetrad each end up in a different ___________________________. Check for Understanding This diagram shows how chromosomes separate during meiosis. Did these chromosomes cross over? How can you tell? Gregor Mendel Gregor Mendel was an Austrian monk who studied the traits of the pea plants in his garden. He is often considered “The Father of Genetics.” His work was very important to the understanding of genetics. Mendelian Genetics Mendelian genetics only works with ____________________ that are controlled by one _________________. The presence of different ___________________ of that _________________ determines the ____________________. 2 Suppose this gene is the gene for a dimpled chin. A dimpled chin is a trait that is only controlled by one gene, meaning that there is one location (loci) on this homologous pair of chromosomes that is for the dimpled chin gene. There are no other genes anywhere, on any chromosome, that control the dimpled chin trait. Some traits, like height and skin color, are controlled by many genes. For these traits, there are several genes with different loci. The genes may even be on different chromosomes. Homozygous and heterozygous describe the genotype of an organism. An organism that is __________________________ for a trait has two copies of the same allele. If two dominant alleles are present, the organism is __________________________ ______________________ for that trait. If two recessive alleles are present, the organism is __________________________ ______________________ (PP or aa). An organism that is __________________________ for a trait has two different alleles, and only the dominant allele is expressed in the phenotype (Bb). Example Dracula has a widow’s peak, which is a dominant trait. We know Dracula must have at least one dominant allele for a widow’s peak (W). Dracula’s genotype could be homozygous dominant (WW) or heterozygous (Ww). If Dracula had no widow’s peak, he would be homozygous recessive (ww) Check for Understanding Having a dimple (or a cleft) in your chin is a dominant trait. The recessive trait is having a smooth or straight chin. What are the possible genotypes for Eminem’s chin? Use the letter D for the dominant allele and d for the recessive allele. 3 Recall: Chromosomes _________ ________________________________ are the X and Y chromosomes that determine an individual’s sex __________________________________ are the rest of an individual’s chromosomes Humans have 23 pairs of chromosomes: One pair of sex chromosomes And 22 pairs of autosomes Sex-Linked Traits Alleles for ______ ___________________ _______________ can be located on either the X or Y chromosome. Most genes for sex-linked traits are located on the X chromosome (Xlinked), simply because the X chromosome has many more genes than the Y chromosome. Example: Colorblindness Example: colorblindness is an X-linked, ___________________________ trait. Since females have two X chromosomes, a female must have two alleles for colorblindness to be colorblind (one on each X chromosome). A female with only one allele for colorblindness is called a carrier, because she will not express the colorblind phenotype, but she may pass the colorblind allele to her offspring. Since males only have one X chromosome, they will be colorblind if they have the allele for colorblindness. The genotype of a male affected with colorblindness would be _________________. The genotype of a carrier female would be ______________________. The genotype of female affected with colorblindness would be ________________________. X-linked __________________________ traits are called recessive because the other, normal _____________________ on the second X chromosome in females can __________________ the trait. 4 So, a female with two X chromosomes must have ________________ copies of the allele to express the X-linked recessive phenotype. The Y chromosome has ________________genes than the X chromosome, so it cannot mask the allele on the X chromosome. The X and Y chromosomes are not homologous. Check for Understanding If a woman who is colorblind has a son with a man who is not colorblind, what is the probability that the son will be colorblind? If a colorblind woman has a daughter with a colorblind man, what is the probability that the daughter will be colorblind? Punnett Squares A __________________ _______________ is a diagram that shows the gene combinations that might occur when two parents make offspring (children). The _______________________ of one parent is listed across the top, and the ______________________ of the other parent is listed down the left side. The four boxes inside represent the_________________________ ____________________________of the offspring. Let’s fill in this Punnett square together. Let’s say the trait we are looking at is for height in pea plants. T represents the dominant tall allele, and t represents the recessive short allele. What are the genotypes of the parents in this Punnett square? What is the probability of having tall offspring? What is the probability of having short offspring? 5 X-Linked Punnett Square _________________________________ is an X-linked genetic disease. It causes blood to clot improperly, so people with the disease bleed longer than people without the disease. In this Punnett square, we are crossing a ____________________ ________________________ with a male who has hemophilia. 6