* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Amide Bond Formation
Structural alignment wikipedia , lookup
Bimolecular fluorescence complementation wikipedia , lookup
Homology modeling wikipedia , lookup
Protein folding wikipedia , lookup
Protein domain wikipedia , lookup
Protein purification wikipedia , lookup
Polycomb Group Proteins and Cancer wikipedia , lookup
Nuclear magnetic resonance spectroscopy of proteins wikipedia , lookup
Circular dichroism wikipedia , lookup
Protein moonlighting wikipedia , lookup
Western blot wikipedia , lookup
Protein–protein interaction wikipedia , lookup
Alpha helix wikipedia , lookup
List of types of proteins wikipedia , lookup
Protein structure prediction wikipedia , lookup
Protein mass spectrometry wikipedia , lookup
Amide Bond Formation • Amide bonds form upon reaction of carboxylic acids with ammonia, primary amines or secondary amines. • When amide bonds form between amino acids we call it a peptide bond. 1 Amino Acids 2 Proteins • • • Proteins are polymers of amino acid monomers held together by peptide bonds. Roles of proteins: – Gene expression is due to proteins – Almost all enzymes are proteins – Many hormones are proteins or peptides – Proteins form structural tissue – Storage and transportation of many molecules is possible due to proteins (think back to passive transport of hydrophilic molecules in and out of cells) – The immune system uses proteins to identify and attack foreign invaders such as bacteria Structure of proteins: – Primary Structure: refers to the sequence of amino acids in a protein chain held together by amide bonds (peptide bonds) – Secondary Structure: refers to the regular and repeating spatial organization of neighboring segments of protein chains (either the alpha-helix or the beta-sheet). 3